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Incomplete Intervention Description, Incorrect Exploratory Outcome Data, and Incorrect Axis Labels

Incomplete Intervention Description, Incorrect Exploratory Outcome Data, and Incorrect Axis Labels Letters at 96 hours (P = .03). There was a 60% probability that any ran- Figure. Worst-Rank/Best-Rank Post Hoc mSOFA Analysis Using dom patient from the placebo group had a higher mSOFA score Mann-Whitney Rank Sum Test than any random patient from the vitamin C group. Although the result at 96 hours differs from the primary analysis, this Vitamin C Placebo analysis is post hoc and exploratory and does not change the conclusion of the study. Alpha A. Fowler III, MD Bernard J. Fisher, BS, MS Markos G. Kashiouris, MD, MPH Author Affiliations: Division of Pulmonary Disease and Critical Care Medicine, Virginia Commonwealth University, Richmond. Corresponding Author: Alpha A. Fowler III, MD, Division of Pulmonary Disease and Critical Care Medicine, Department of Internal Medicine, Virginia Commonwealth University School of Medicine, 1200 E Broad St, Richmond, VA 23298 (alpha.fowler@vcuhealth.org). 0 48 96 Hours After Vitamin C Infusion Conflict of Interest Disclosures: Dr Fowler reported receiving grants from the National Heart, Lung, and Blood Institute, an honorarium from Virginia Tech School of Medicine, nonmonetary support from Virginia Commonwealth A modified Sequential Organ Failure Assessment (mSOFA) value of 20 was University’s National Center for Advancing Translational Sciences, and study assigned to patients http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Incomplete Intervention Description, Incorrect Exploratory Outcome Data, and Incorrect Axis Labels

JAMA , Volume 323 (8) – Feb 25, 2020

Incomplete Intervention Description, Incorrect Exploratory Outcome Data, and Incorrect Axis Labels

Abstract

Letters at 96 hours (P = .03). There was a 60% probability that any ran- Figure. Worst-Rank/Best-Rank Post Hoc mSOFA Analysis Using dom patient from the placebo group had a higher mSOFA score Mann-Whitney Rank Sum Test than any random patient from the vitamin C group. Although the result at 96 hours differs from the primary analysis, this Vitamin C Placebo analysis is post hoc and exploratory and does not change the conclusion of the study. Alpha A. Fowler III, MD Bernard J. Fisher, BS, MS...
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Publisher
American Medical Association
Copyright
Copyright 2020 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2020.0373
Publisher site
See Article on Publisher Site

Abstract

Letters at 96 hours (P = .03). There was a 60% probability that any ran- Figure. Worst-Rank/Best-Rank Post Hoc mSOFA Analysis Using dom patient from the placebo group had a higher mSOFA score Mann-Whitney Rank Sum Test than any random patient from the vitamin C group. Although the result at 96 hours differs from the primary analysis, this Vitamin C Placebo analysis is post hoc and exploratory and does not change the conclusion of the study. Alpha A. Fowler III, MD Bernard J. Fisher, BS, MS Markos G. Kashiouris, MD, MPH Author Affiliations: Division of Pulmonary Disease and Critical Care Medicine, Virginia Commonwealth University, Richmond. Corresponding Author: Alpha A. Fowler III, MD, Division of Pulmonary Disease and Critical Care Medicine, Department of Internal Medicine, Virginia Commonwealth University School of Medicine, 1200 E Broad St, Richmond, VA 23298 (alpha.fowler@vcuhealth.org). 0 48 96 Hours After Vitamin C Infusion Conflict of Interest Disclosures: Dr Fowler reported receiving grants from the National Heart, Lung, and Blood Institute, an honorarium from Virginia Tech School of Medicine, nonmonetary support from Virginia Commonwealth A modified Sequential Organ Failure Assessment (mSOFA) value of 20 was University’s National Center for Advancing Translational Sciences, and study assigned to patients

Journal

JAMAAmerican Medical Association

Published: Feb 25, 2020

References