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Incidence of Allergic Reactions to Hydrocortisone-17-Butyrate in Standard Patch Test Series

Incidence of Allergic Reactions to Hydrocortisone-17-Butyrate in Standard Patch Test Series Abstract To the Editor.— The number of cases published on contact allergy to topical corticosteroids has increased rapidly in the past few years.1 This could suggest that physicians are more aware of the possibility of contact allergy to corticosteroids and/or that the actual prevalence of this condition has increased. In a recent study, we observed an increase in incidence of allergic patch test reactions to hydrocortisone-17-butyrate in a 6-month study in 1989 and 1990 compared with an identical period in 1988 and 1989.2 Therefore, we performed a retrospective study on allergic reactions to hydrocortisone-17-butyrate in standard series in the years 1986 through 1989, including our earlier data from 1986 and 1987,3 and compared the number of allergic reactions to hydrocortisone-17-butyrate to that of other allergens in the standard patch test series. Subjects and Methods.— Inpatients and outpatients undergoing patch testing due to suspected contact hypersensitivity in the department References 1. Dooms-Goossens A. Contact dermatitis to topical corticosteroids: diagnostic problems . In: Menné T, Maibach HI, eds. Exogenous Dermatoses: Environmental Dermatitis . Boca Raton, Fla: CRC Press Inc; 1991:299-310. 2. Lauerma AI. Screening for corticosteroid contact sensitivity: comparison of tixocortol pivalate, hydrocortisone-17-butyrate and hydrocortisone . Contact Dermatitis. 1991;24:123-130.Crossref 3. Reitamo S, Lauerma AI, Förström L. Detection of contact hypersensitivity to topical corticosteroids with hydrocortisone-17-butyrate . Contact Dermatitis. 1989;21:159-165.Crossref 4. Wilkinson DS, Freger S, Magnusson B, et al. Terminology of contact dermatitis . Acta Derm Venereol (Stockh) . 1970;50:287-292. 5. Wilkinson SM, Cartwright PH, English JSC. Hydrocortisone: an important cutaneous allergen . Lancet . 1991;337:761-762.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Incidence of Allergic Reactions to Hydrocortisone-17-Butyrate in Standard Patch Test Series

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Incidence of Allergic Reactions to Hydrocortisone-17-Butyrate in Standard Patch Test Series

Abstract

Abstract To the Editor.— The number of cases published on contact allergy to topical corticosteroids has increased rapidly in the past few years.1 This could suggest that physicians are more aware of the possibility of contact allergy to corticosteroids and/or that the actual prevalence of this condition has increased. In a recent study, we observed an increase in incidence of allergic patch test reactions to hydrocortisone-17-butyrate in a 6-month study in 1989 and 1990 compared with...
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Publisher
American Medical Association
Copyright
Copyright © 1992 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1992.01680120151029
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor.— The number of cases published on contact allergy to topical corticosteroids has increased rapidly in the past few years.1 This could suggest that physicians are more aware of the possibility of contact allergy to corticosteroids and/or that the actual prevalence of this condition has increased. In a recent study, we observed an increase in incidence of allergic patch test reactions to hydrocortisone-17-butyrate in a 6-month study in 1989 and 1990 compared with an identical period in 1988 and 1989.2 Therefore, we performed a retrospective study on allergic reactions to hydrocortisone-17-butyrate in standard series in the years 1986 through 1989, including our earlier data from 1986 and 1987,3 and compared the number of allergic reactions to hydrocortisone-17-butyrate to that of other allergens in the standard patch test series. Subjects and Methods.— Inpatients and outpatients undergoing patch testing due to suspected contact hypersensitivity in the department References 1. Dooms-Goossens A. Contact dermatitis to topical corticosteroids: diagnostic problems . In: Menné T, Maibach HI, eds. Exogenous Dermatoses: Environmental Dermatitis . Boca Raton, Fla: CRC Press Inc; 1991:299-310. 2. Lauerma AI. Screening for corticosteroid contact sensitivity: comparison of tixocortol pivalate, hydrocortisone-17-butyrate and hydrocortisone . Contact Dermatitis. 1991;24:123-130.Crossref 3. Reitamo S, Lauerma AI, Förström L. Detection of contact hypersensitivity to topical corticosteroids with hydrocortisone-17-butyrate . Contact Dermatitis. 1989;21:159-165.Crossref 4. Wilkinson DS, Freger S, Magnusson B, et al. Terminology of contact dermatitis . Acta Derm Venereol (Stockh) . 1970;50:287-292. 5. Wilkinson SM, Cartwright PH, English JSC. Hydrocortisone: an important cutaneous allergen . Lancet . 1991;337:761-762.Crossref

Journal

Archives of Dermatology – American Medical Association

Published: Feb 1, 1992

References

  • Exogenous Dermatoses: Environmental Dermatitis
    Dooms-Goossens A
  • Screening for corticosteroid contact sensitivity: comparison of tixocortol pivalate, hydrocortisone-17-butyrate and hydrocortisone
    Lauerma AI
  • Detection of contact hypersensitivity to topical corticosteroids with hydrocortisone-17-butyrate
    Reitamo S, Lauerma AI, Förström L
  • Terminology of contact dermatitis
    Wilkinson DS, Freger S, Magnusson B, et al
  • Hydrocortisone: an important cutaneous allergen
    Wilkinson SM, Cartwright PH, English JSC