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Implications of Suspicious Findings in Breast Cancer Screening

Implications of Suspicious Findings in Breast Cancer Screening Abstract Breast cancer screening, performed on asymptomatic women over 35 years of age, has identified 32 breast cancers in 30 of 4,500 women screened. Screening included a physical examination by trained technologists, thermography, and xeromammography. This represents 26% of the biopsies performed (116). Results of xeromammography were suspicious in 24 cases (80%), and results of physical examination were suspicious in 11 (37%). Only six were suspicious by both methods, with one other having changes that were considered benign. Fourteen (44%) were microinvasive or noninvasive. Only two (6%) had axillary metastases. Breast cancer detected by screening is in its "early" stages and is usually well localized. Operative management, including removal of the entire breast, has a significant potential for cure. Thirty patients with changes considered suspicious have not yet had biopsies. Improved overall survival depends on appropriate management of all patients screened. References 1. Donegan WL, Say CG: Invasive carcinoma of the breast: Prognostic significance of tumor size and involved axillary lymph nodes . Cancer 34:468-471, 1974.Crossref 2. Crile G Jr: Relationship of the size of the tumor and the size of involved nodes to survival . Am J Surg 124:35-38, 1972.Crossref 3. Haberman JD: The role of thermography in breast cancer detection . Proc Natl Cancer Conf 6:157-161, 1970. 4. Wallace JD, Dodd GD: Thermography in the diagnosis of breast cancer . Radiology 91:679-685, 1968.Crossref 5. Isard HJ, Becker W, Shilo R, et al: Breast thermography after four years and 10,000 studies . Am J Roentgenol Radium Ther Nucl Med 115:811-820, 1972.Crossref 6. Egan RL: Mammography , ed 2. Springfield, Ill, Charles C Thomas Publishers, 1972. 7. Witten DM, Thurber DL: Mammography as a routine screening examination for detecting breast cancer . Am J Roentgenol Radium Ther Nucl Med 92:14-20, 1964. 8. Furnival IG, Stewart HJ, Weddell JM, et al: Accuracy of screening methods for the diagnosis of breast disease . Br Med J 4:461-463, 1970.Crossref 9. Wolfe JN: Analysis of 462 breast carcinomas . Am J Roentgenol Radium Ther Nucl Med 121:846-853, 1974.Crossref 10. Gilbertson JD, Randall MG, Fingerhut AG: Evaluation of roentgen exposure in mammography: I. Six views . Radiology 95:383-394, 1970.Crossref 11. Palmer RC, Egan RL, Barrett BJ: Preliminary evaluation of absorbed dose in mammography: Six views . Radiology 95:395-397, 1970.Crossref 12. Ostrum BJ, Becker W, Isard HJ: Low dose mammography . Radiology 109:323-326, 1973.Crossref 13. Rothenberg LN, Kirch RLA, Snyder R: Patient exposures from film and xeroradiographic mammographic techniques. Read before the 60th Scientific Assembly and Annual Meeting of the Radiological Society of North America, Chicago, 1974. 14. Holleb AI, Venet L, Day E, et al: Breast cancer detected by routine physical examination: Three-year survey of the Strang Cancer Prevention Clinic . NY J Med 60:823-827, 1960. 15. Venet L, Strax P, Venet W, et al: Adequacies and inadequacies of breast examinations by physicians . Cancer 24:1187-1191, 1969.Crossref 16. Wheeler JE, Enterline HT, Roseman JM, et al: Lobular carcinoma in situ of the breast: Long-term follow-up . Cancer 34:554-563, 1974.Crossref 17. Hayward J: Conservative surgery in the treatment of early breast cancer . Br J Surg 61:770-771, 1974.Crossref 18. Burn JI: "Early" breast cancer: The Hammersmith trial . Br J Surg 61:762-765, 1974.Crossref 19. Urban JA: Treatment of early cancer of the breast . Postgrad Med 27:389-393, 1960. 20. Wanebo HJ, Huvos AG, Urban JA: Treatment of minimal breast cancer . Cancer 33:349-357, 1974.Crossref 21. Gallagher HS, Martin JE: Early phases in the development of breast cancer . Cancer 24:1170-1178, 1969.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

Implications of Suspicious Findings in Breast Cancer Screening

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Publisher
American Medical Association
Copyright
Copyright © 1975 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1975.01360140047010
Publisher site
See Article on Publisher Site

Abstract

Abstract Breast cancer screening, performed on asymptomatic women over 35 years of age, has identified 32 breast cancers in 30 of 4,500 women screened. Screening included a physical examination by trained technologists, thermography, and xeromammography. This represents 26% of the biopsies performed (116). Results of xeromammography were suspicious in 24 cases (80%), and results of physical examination were suspicious in 11 (37%). Only six were suspicious by both methods, with one other having changes that were considered benign. Fourteen (44%) were microinvasive or noninvasive. Only two (6%) had axillary metastases. Breast cancer detected by screening is in its "early" stages and is usually well localized. Operative management, including removal of the entire breast, has a significant potential for cure. Thirty patients with changes considered suspicious have not yet had biopsies. Improved overall survival depends on appropriate management of all patients screened. References 1. Donegan WL, Say CG: Invasive carcinoma of the breast: Prognostic significance of tumor size and involved axillary lymph nodes . Cancer 34:468-471, 1974.Crossref 2. Crile G Jr: Relationship of the size of the tumor and the size of involved nodes to survival . Am J Surg 124:35-38, 1972.Crossref 3. Haberman JD: The role of thermography in breast cancer detection . Proc Natl Cancer Conf 6:157-161, 1970. 4. Wallace JD, Dodd GD: Thermography in the diagnosis of breast cancer . Radiology 91:679-685, 1968.Crossref 5. Isard HJ, Becker W, Shilo R, et al: Breast thermography after four years and 10,000 studies . Am J Roentgenol Radium Ther Nucl Med 115:811-820, 1972.Crossref 6. Egan RL: Mammography , ed 2. Springfield, Ill, Charles C Thomas Publishers, 1972. 7. Witten DM, Thurber DL: Mammography as a routine screening examination for detecting breast cancer . Am J Roentgenol Radium Ther Nucl Med 92:14-20, 1964. 8. Furnival IG, Stewart HJ, Weddell JM, et al: Accuracy of screening methods for the diagnosis of breast disease . Br Med J 4:461-463, 1970.Crossref 9. Wolfe JN: Analysis of 462 breast carcinomas . Am J Roentgenol Radium Ther Nucl Med 121:846-853, 1974.Crossref 10. Gilbertson JD, Randall MG, Fingerhut AG: Evaluation of roentgen exposure in mammography: I. Six views . Radiology 95:383-394, 1970.Crossref 11. Palmer RC, Egan RL, Barrett BJ: Preliminary evaluation of absorbed dose in mammography: Six views . Radiology 95:395-397, 1970.Crossref 12. Ostrum BJ, Becker W, Isard HJ: Low dose mammography . Radiology 109:323-326, 1973.Crossref 13. Rothenberg LN, Kirch RLA, Snyder R: Patient exposures from film and xeroradiographic mammographic techniques. Read before the 60th Scientific Assembly and Annual Meeting of the Radiological Society of North America, Chicago, 1974. 14. Holleb AI, Venet L, Day E, et al: Breast cancer detected by routine physical examination: Three-year survey of the Strang Cancer Prevention Clinic . NY J Med 60:823-827, 1960. 15. Venet L, Strax P, Venet W, et al: Adequacies and inadequacies of breast examinations by physicians . Cancer 24:1187-1191, 1969.Crossref 16. Wheeler JE, Enterline HT, Roseman JM, et al: Lobular carcinoma in situ of the breast: Long-term follow-up . Cancer 34:554-563, 1974.Crossref 17. Hayward J: Conservative surgery in the treatment of early breast cancer . Br J Surg 61:770-771, 1974.Crossref 18. Burn JI: "Early" breast cancer: The Hammersmith trial . Br J Surg 61:762-765, 1974.Crossref 19. Urban JA: Treatment of early cancer of the breast . Postgrad Med 27:389-393, 1960. 20. Wanebo HJ, Huvos AG, Urban JA: Treatment of minimal breast cancer . Cancer 33:349-357, 1974.Crossref 21. Gallagher HS, Martin JE: Early phases in the development of breast cancer . Cancer 24:1170-1178, 1969.Crossref

Journal

Archives of SurgeryAmerican Medical Association

Published: Aug 1, 1975

References