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Implantable Spinal Cord Stimulator Allows Voluntary Movement in Individuals With Lower-Extremity Paralysis

Implantable Spinal Cord Stimulator Allows Voluntary Movement in Individuals With Lower-Extremity... News & Analysis Lab, Field, & Clinic Implantable Spinal Cord Stimulator Allows Voluntary Movement in Individuals With Lower-Extremity Paralysis Jill Jin, MD, MPH n “off-the-shelf” implantable spinal In2009,afterpromisingresultsfromear- plainedSusanHarkema,PhD,thestudy’slead cord stimulator currently used to lier studies using this device on animals with investigator.However,totheastonishmentof A treat chronic neuropathic pain may chronicparalysis,agroupofresearchersfrom the team, all 3 were able to regain voluntary provide a novel strategy to foster recovery of the University of Louisville in Kentucky met motor function. neurologicalfunctioninpatientswithchronic withagroupofinternationalexpertsinthefield Howcantheseresultsbeexplained?“We complete paralysis from spinal cord injury. anddecidedtoimplantthedeviceinahuman know that the spinal cord is an extremely so- Arecentlypublishedcaseseriesinvolving patient.Thispatient,a23-year-oldmanwitha phisticated and complex network,” said 4patientswithcompletelower-extremitymo- C7 spinal cord injury from a motor vehicle ac- Harkema. “The primary driving force for torparalysisshowedthatepiduralspinalcord cident, then received intensive movement movement of the lower extremities comes stimulation in conjunction with intensive training with spinal cord stimulation from the from the periphery, not the brain, so some- movement training over a period of up to 2 device. To the surprise of the entire team, af- thing in this underlying network must still be yearsresultedintheabilitytointentionallyex- ter 7 months of training, the patient was able working in these patients with complete pa- ecutemovementsofthelowerextremities,in- to lift his legs and http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Implantable Spinal Cord Stimulator Allows Voluntary Movement in Individuals With Lower-Extremity Paralysis

JAMA , Volume 312 (2) – Jul 9, 2014

Implantable Spinal Cord Stimulator Allows Voluntary Movement in Individuals With Lower-Extremity Paralysis

Abstract

News & Analysis Lab, Field, & Clinic Implantable Spinal Cord Stimulator Allows Voluntary Movement in Individuals With Lower-Extremity Paralysis Jill Jin, MD, MPH n “off-the-shelf” implantable spinal In2009,afterpromisingresultsfromear- plainedSusanHarkema,PhD,thestudy’slead cord stimulator currently used to lier studies using this device on animals with investigator.However,totheastonishmentof A treat chronic neuropathic pain may...
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Publisher
American Medical Association
Copyright
Copyright 2014 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2014.7508
Publisher site
See Article on Publisher Site

Abstract

News & Analysis Lab, Field, & Clinic Implantable Spinal Cord Stimulator Allows Voluntary Movement in Individuals With Lower-Extremity Paralysis Jill Jin, MD, MPH n “off-the-shelf” implantable spinal In2009,afterpromisingresultsfromear- plainedSusanHarkema,PhD,thestudy’slead cord stimulator currently used to lier studies using this device on animals with investigator.However,totheastonishmentof A treat chronic neuropathic pain may chronicparalysis,agroupofresearchersfrom the team, all 3 were able to regain voluntary provide a novel strategy to foster recovery of the University of Louisville in Kentucky met motor function. neurologicalfunctioninpatientswithchronic withagroupofinternationalexpertsinthefield Howcantheseresultsbeexplained?“We complete paralysis from spinal cord injury. anddecidedtoimplantthedeviceinahuman know that the spinal cord is an extremely so- Arecentlypublishedcaseseriesinvolving patient.Thispatient,a23-year-oldmanwitha phisticated and complex network,” said 4patientswithcompletelower-extremitymo- C7 spinal cord injury from a motor vehicle ac- Harkema. “The primary driving force for torparalysisshowedthatepiduralspinalcord cident, then received intensive movement movement of the lower extremities comes stimulation in conjunction with intensive training with spinal cord stimulation from the from the periphery, not the brain, so some- movement training over a period of up to 2 device. To the surprise of the entire team, af- thing in this underlying network must still be yearsresultedintheabilitytointentionallyex- ter 7 months of training, the patient was able working in these patients with complete pa- ecutemovementsofthelowerextremities,in- to lift his legs and

Journal

JAMAAmerican Medical Association

Published: Jul 9, 2014

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