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Immunologic Studies in Lichen Myxedematosus

Immunologic Studies in Lichen Myxedematosus Abstract A patient with lichen myxedematosus of 13 years' duration has experienced stabilization or regression of the disease. The long duration of clinical well-being suggests that this patient is not suffering from a variant of multiple myeloma. Serum protein studies reveal an abnormal serum protein in the γ-globulin region. Immunoglobulin IgA levels in serum are abnormally high. Circulating antibody responses after immunization with Vi and brucellin antigens and delayed hypersensitivity responses in this patient are apparently normal. References 1. Prepared from Escherichia coli. 2. McCarthy, J.T, et al: An Abnormal Serum Globulin in Lichen Myxedematosus , Arch Derm 89:446-450, 1964.Crossref 3. James, K., et al: Lichen Myxedematosus: A Rare Dermatologic Disease Associated With a Unique Serum Paraprotein , Clin Res 14:138, 1966. 4. Fahey, J.L.; and McKelvey, E.M.: Quantitative Determination of Serum Immunoglobulins in Antibody-Agar Plates , J Immun 94:84-90, 1965. 5. Landy, M.; et al: Studies on the O Antigen of Salmonella typhosa: II. Immunological Properties of the Purified Antigen , J Immun 74:466-478, 1955. 6. Huddleson, I.F.; and Abell, E.: Rapid Macroscopic Agglutination for the Serum Diagnosis of Bang's Abortion Disease , J Infect Dis 42:242-247, 1928.Crossref 7. Welch, H.; and Stuart, C.A.: A Rapid Slide Test for the Serologic Diagnosis of Typhoid and Paratyphoid Fevers , J Lab Clin Med 21:411-417, 1936. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Immunologic Studies in Lichen Myxedematosus

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Publisher
American Medical Association
Copyright
Copyright © 1967 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1967.01600340030006
Publisher site
See Article on Publisher Site

Abstract

Abstract A patient with lichen myxedematosus of 13 years' duration has experienced stabilization or regression of the disease. The long duration of clinical well-being suggests that this patient is not suffering from a variant of multiple myeloma. Serum protein studies reveal an abnormal serum protein in the γ-globulin region. Immunoglobulin IgA levels in serum are abnormally high. Circulating antibody responses after immunization with Vi and brucellin antigens and delayed hypersensitivity responses in this patient are apparently normal. References 1. Prepared from Escherichia coli. 2. McCarthy, J.T, et al: An Abnormal Serum Globulin in Lichen Myxedematosus , Arch Derm 89:446-450, 1964.Crossref 3. James, K., et al: Lichen Myxedematosus: A Rare Dermatologic Disease Associated With a Unique Serum Paraprotein , Clin Res 14:138, 1966. 4. Fahey, J.L.; and McKelvey, E.M.: Quantitative Determination of Serum Immunoglobulins in Antibody-Agar Plates , J Immun 94:84-90, 1965. 5. Landy, M.; et al: Studies on the O Antigen of Salmonella typhosa: II. Immunological Properties of the Purified Antigen , J Immun 74:466-478, 1955. 6. Huddleson, I.F.; and Abell, E.: Rapid Macroscopic Agglutination for the Serum Diagnosis of Bang's Abortion Disease , J Infect Dis 42:242-247, 1928.Crossref 7. Welch, H.; and Stuart, C.A.: A Rapid Slide Test for the Serologic Diagnosis of Typhoid and Paratyphoid Fevers , J Lab Clin Med 21:411-417, 1936.

Journal

Archives of DermatologyAmerican Medical Association

Published: Apr 1, 1967

References