Key PointsQuestionWhat is the immunogenicity of COVID-19 messenger RNA (mRNA) vaccines in pregnant and lactating women? FindingsIn this cohort study involving 103 women who received a COVID-19 mRNA vaccine, 30 of whom were pregnant and 16 of whom were lactating, immunogenicity was demonstrated in all, and vaccine-elicited antibodies were found in infant cord blood and breast milk. Pregnant and nonpregnant vaccinated women developed cross-reactive immune responses against SARS-CoV-2 variants of concern. MeaningIn a small convenience sample, COVID-19 mRNA vaccines were immunogenic in pregnant and lactating women and induced immune responses against SARS-CoV-2 variants.
JAMA – American Medical Association
Published: Jun 15, 2021