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Identifying the Primary Site in Metastatic Cancer of Unknown Origin

Identifying the Primary Site in Metastatic Cancer of Unknown Origin Two hundred sixty-six patients with metastatic nonsquamous carcinoma of unknown origin underwent upper and lower gastrointestinal series, intravenous pyelograms, and chest roentgenograms (CR) for location of a primary cancer site. Of 129 identified primary cancer sites, only 22 were verified antemortem, whereas necropsy disclosed 25 cases with falsepositive examination results. The CR patterns thought typical for lung cancer (eg, single mass lesion and hilar or mediastinal adenopathy) were often shown (43%) to represent metastatic lesions. Because contrast roentgenographic studies are costly, uncomfortable, of low yield, and often misleading, they should be limited to cases with specific organ dysfunction. (JAMA 241:381-383, 1979) http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Identifying the Primary Site in Metastatic Cancer of Unknown Origin

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References (13)

Publisher
American Medical Association
Copyright
Copyright © 1979 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1979.03290300023020
Publisher site
See Article on Publisher Site

Abstract

Two hundred sixty-six patients with metastatic nonsquamous carcinoma of unknown origin underwent upper and lower gastrointestinal series, intravenous pyelograms, and chest roentgenograms (CR) for location of a primary cancer site. Of 129 identified primary cancer sites, only 22 were verified antemortem, whereas necropsy disclosed 25 cases with falsepositive examination results. The CR patterns thought typical for lung cancer (eg, single mass lesion and hilar or mediastinal adenopathy) were often shown (43%) to represent metastatic lesions. Because contrast roentgenographic studies are costly, uncomfortable, of low yield, and often misleading, they should be limited to cases with specific organ dysfunction. (JAMA 241:381-383, 1979)

Journal

JAMAAmerican Medical Association

Published: Jan 26, 1979

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