Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Hypotensive Reaction Following the Use of Glucagon

Hypotensive Reaction Following the Use of Glucagon Abstract There are no reported instances of sensitivity to glucagon. Recently we observed a severe hypotensive reaction immediately following the intravenous administration of glucagon. With the increased interest in glucagon, it appears advisable to report this reaction. Report of Cases The patient is a 52-year-old divorced housewife with a history of good physical health. Five years prior to this admission, on two separate occasions separated by two or three months, she received six to eight subcoma doses of insulin during psychiatric treatment at another location. Routine physical, neurological, and laboratory examinations at the time of admission to the Henry Phipps Psychiatric Clinic were within normal limits. Her diagnosis during this hospitalization was paranoid personality reaction.The glucagon* was administered as a part of a study of the response to glucagon in a large group of persons. While the patient was in a fasting state and supine, a blood specimen was withdrawn References 1. Insulin diluting fluid is the diluent for both insulin and glucagon. 2. Kirtley, W. R.; Waife, S. O.; Helmer, O. M., and Peck, F. B.: Effect of Purified Glucagon (Hyperglycemic-Glycogenolytic Factor, HGF) on Carbohydrate and Corticoid Metabolism in Normal and Diabetic Subjects , Diabetes 2:345, 1953. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Internal Medicine American Medical Association

Hypotensive Reaction Following the Use of Glucagon

Loading next page...
 
/lp/american-medical-association/hypotensive-reaction-following-the-use-of-glucagon-vwe5gvixsr
Publisher
American Medical Association
Copyright
Copyright © 1957 American Medical Association. All Rights Reserved.
ISSN
0888-2479
DOI
10.1001/archinte.1957.00260050145015
Publisher site
See Article on Publisher Site

Abstract

Abstract There are no reported instances of sensitivity to glucagon. Recently we observed a severe hypotensive reaction immediately following the intravenous administration of glucagon. With the increased interest in glucagon, it appears advisable to report this reaction. Report of Cases The patient is a 52-year-old divorced housewife with a history of good physical health. Five years prior to this admission, on two separate occasions separated by two or three months, she received six to eight subcoma doses of insulin during psychiatric treatment at another location. Routine physical, neurological, and laboratory examinations at the time of admission to the Henry Phipps Psychiatric Clinic were within normal limits. Her diagnosis during this hospitalization was paranoid personality reaction.The glucagon* was administered as a part of a study of the response to glucagon in a large group of persons. While the patient was in a fasting state and supine, a blood specimen was withdrawn References 1. Insulin diluting fluid is the diluent for both insulin and glucagon. 2. Kirtley, W. R.; Waife, S. O.; Helmer, O. M., and Peck, F. B.: Effect of Purified Glucagon (Hyperglycemic-Glycogenolytic Factor, HGF) on Carbohydrate and Corticoid Metabolism in Normal and Diabetic Subjects , Diabetes 2:345, 1953.

Journal

A.M.A. Archives of Internal MedicineAmerican Medical Association

Published: May 1, 1957

References