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Hypertrophic Lichen Planus Treated by Local Injection of Prednisolone

Hypertrophic Lichen Planus Treated by Local Injection of Prednisolone Abstract This report concerns the successful treatment of the hypertrophic type of lichen planus by the local injection of prednisolone suspension. Cessation of severe pruritus and the involution of hypertrophy in these lesions were accomplished in all lesions treated by this method. Method A sterile aqueous suspension containing 25 mg. per cc. prednisolone* was used. It was found that the 24-gauge hypodermic needle allowed the particles in suspension to pass through without stoppage. The lesions were treated at weekly intervals, and no more than 1 cc. (25 mg.) of the prednisolone suspension was injected in one week. The amount injected into any one lesion varied from 0.3 cc. to 0.5 cc. Treatment Three patients with typical lesions of lichen planus of the verrucous or hypertrophic type were treated. One patient was a Negro housewife, age 42, with some 30 lesions on the lower limbs, varying in size from 6 References 1. The prednisolone suspension (Meticortelone) used in this study was supplied by Dr. Harry Pifer, Division of Clinical Research, Schering Corporation, Bloomfield, N. J. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Dermatology American Medical Association

Hypertrophic Lichen Planus Treated by Local Injection of Prednisolone

A.M.A. Archives of Dermatology , Volume 75 (2) – Feb 1, 1957

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Publisher
American Medical Association
Copyright
Copyright © 1957 American Medical Association. All Rights Reserved.
ISSN
0096-5359
DOI
10.1001/archderm.1957.01550140108018
Publisher site
See Article on Publisher Site

Abstract

Abstract This report concerns the successful treatment of the hypertrophic type of lichen planus by the local injection of prednisolone suspension. Cessation of severe pruritus and the involution of hypertrophy in these lesions were accomplished in all lesions treated by this method. Method A sterile aqueous suspension containing 25 mg. per cc. prednisolone* was used. It was found that the 24-gauge hypodermic needle allowed the particles in suspension to pass through without stoppage. The lesions were treated at weekly intervals, and no more than 1 cc. (25 mg.) of the prednisolone suspension was injected in one week. The amount injected into any one lesion varied from 0.3 cc. to 0.5 cc. Treatment Three patients with typical lesions of lichen planus of the verrucous or hypertrophic type were treated. One patient was a Negro housewife, age 42, with some 30 lesions on the lower limbs, varying in size from 6 References 1. The prednisolone suspension (Meticortelone) used in this study was supplied by Dr. Harry Pifer, Division of Clinical Research, Schering Corporation, Bloomfield, N. J.

Journal

A.M.A. Archives of DermatologyAmerican Medical Association

Published: Feb 1, 1957

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