Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

Histological Findings in Neonatal Hepatitis

Histological Findings in Neonatal Hepatitis Abstract Since the original descriptions by J. Craig, S. Gellis, and D. Hsia; J. Craig and B. Landing; and by D. Danks and M. Bodian, giant multinucleated hepatic cells have been regarded as the histologic feature of neonatal hepatitis. The histologic material of 150 cases of prolonged obstructive jaundice obtained at the Hopital des Enfants Malades, Paris, has been recently reviewed, in order to investigate the diagnostic value of the following: giant symplasmic cells, ductal proliferation, areas of cellular necrosis, and zones of bile stasis. A diagnosis of complete or partial biliary atresia was made on the basis of cholangiography performed during laparotomy on 100 patients. No obstruction of the extrabiliary tree was found in the remaining 50 patients. These cases were considered a priori as hepatitis. A diagnosis of syphilis, toxoplasmosis, rubella, or cytomegalic inclusion disease was confirmed in some. In most cases the etiology remained unknown. The histological slides http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

Histological Findings in Neonatal Hepatitis

American Journal of Diseases of Children , Volume 123 (4) – Apr 1, 1972

Histological Findings in Neonatal Hepatitis

Abstract

Abstract Since the original descriptions by J. Craig, S. Gellis, and D. Hsia; J. Craig and B. Landing; and by D. Danks and M. Bodian, giant multinucleated hepatic cells have been regarded as the histologic feature of neonatal hepatitis. The histologic material of 150 cases of prolonged obstructive jaundice obtained at the Hopital des Enfants Malades, Paris, has been recently reviewed, in order to investigate the diagnostic value of the following: giant symplasmic cells, ductal proliferation,...
Loading next page...
 
/lp/american-medical-association/histological-findings-in-neonatal-hepatitis-0e0YQZLb1O
Publisher
American Medical Association
Copyright
Copyright © 1972 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1972.02110100031009
Publisher site
See Article on Publisher Site

Abstract

Abstract Since the original descriptions by J. Craig, S. Gellis, and D. Hsia; J. Craig and B. Landing; and by D. Danks and M. Bodian, giant multinucleated hepatic cells have been regarded as the histologic feature of neonatal hepatitis. The histologic material of 150 cases of prolonged obstructive jaundice obtained at the Hopital des Enfants Malades, Paris, has been recently reviewed, in order to investigate the diagnostic value of the following: giant symplasmic cells, ductal proliferation, areas of cellular necrosis, and zones of bile stasis. A diagnosis of complete or partial biliary atresia was made on the basis of cholangiography performed during laparotomy on 100 patients. No obstruction of the extrabiliary tree was found in the remaining 50 patients. These cases were considered a priori as hepatitis. A diagnosis of syphilis, toxoplasmosis, rubella, or cytomegalic inclusion disease was confirmed in some. In most cases the etiology remained unknown. The histological slides

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Apr 1, 1972

There are no references for this article.