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Histologic Findings in the Temporal Bone in Trisomy D (D/D Translocation)

Histologic Findings in the Temporal Bone in Trisomy D (D/D Translocation) Abstract • The temporal bones of an infant in whom the diagnosis of unbalanced trisomy D (D/D translocation) had been made by chromosomal analysis during life were studied histologically. Most of the findings resembled those that have been described by others in trisomy D (13-15) syndrome. A previously unreported abnormality was substrial edema displacing the stria vascularis. The importance of this finding remains to be defined by further study. (Arch Otolaryngol 104:22-25, 1978) References 1. Centerwall WR, Merrell PR: Familial D/D translocation t(13q;14q): Eight members in four generations . Clin Genet 7:91-97, 1975.Crossref 2. Mottet NK, Jensen H: The anomalous embryonic development associated with trisomy 13-15 . Am J Clin Pathol 43:334-347, 1965. 3. Black FO, Sando I, Wagner JA, et al: Middle and inner ear abnormalities: 13-15 (D1) trisomy . Arch Otolaryngol 93:615-619, 1971.Crossref 4. Sando I, Lieberman A, Bergstrom L, et al: Temporal bone histopathological findings in trisomy 13 syndrome . Ann Otol Rhinol Laryngol 84 ( (pt2) , suppl 21):1-20, 1975. 5. Kos AO, Schuknecht HF, Singer JD: Temporal bone studies in 13-15 and 18 trisomy syndromes . Arch Otolaryngol 83:439-445, 1966.Crossref 6. Saito H, Okano Y, Furuta M, et al: Temporal bone findings in trisomy D . Arch Otolaryngol 100:386-389, 1974.Crossref 7. Kelemen G, Hooft C, Kluyskens P: The inner ear in autosomal trisomy . Pract Otorhinolaryngol 30:251-258, 1968. 8. Maniglia AJ, Wolff D, Herques AJ: Congenital deafness in 13-15 trisomy syndrome . Arch Otolaryngol 92:181-188, 1970.Crossref 9. Wright JL, Schuknecht HF: Atrophy of the spiral ligament . Arch Otolaryngol 96:16-21, 1972.Crossref 10. Schuknecht HF: Pathology of the Ear . Cambridge, Mass: Harvard University Press, 1974, chap 1 , pp 16-18. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology American Medical Association

Histologic Findings in the Temporal Bone in Trisomy D (D/D Translocation)

Archives of Otolaryngology , Volume 104 (1) – Jan 1, 1978

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Publisher
American Medical Association
Copyright
Copyright © 1978 American Medical Association. All Rights Reserved.
ISSN
0003-9977
DOI
10.1001/archotol.1978.00790010026006
Publisher site
See Article on Publisher Site

Abstract

Abstract • The temporal bones of an infant in whom the diagnosis of unbalanced trisomy D (D/D translocation) had been made by chromosomal analysis during life were studied histologically. Most of the findings resembled those that have been described by others in trisomy D (13-15) syndrome. A previously unreported abnormality was substrial edema displacing the stria vascularis. The importance of this finding remains to be defined by further study. (Arch Otolaryngol 104:22-25, 1978) References 1. Centerwall WR, Merrell PR: Familial D/D translocation t(13q;14q): Eight members in four generations . Clin Genet 7:91-97, 1975.Crossref 2. Mottet NK, Jensen H: The anomalous embryonic development associated with trisomy 13-15 . Am J Clin Pathol 43:334-347, 1965. 3. Black FO, Sando I, Wagner JA, et al: Middle and inner ear abnormalities: 13-15 (D1) trisomy . Arch Otolaryngol 93:615-619, 1971.Crossref 4. Sando I, Lieberman A, Bergstrom L, et al: Temporal bone histopathological findings in trisomy 13 syndrome . Ann Otol Rhinol Laryngol 84 ( (pt2) , suppl 21):1-20, 1975. 5. Kos AO, Schuknecht HF, Singer JD: Temporal bone studies in 13-15 and 18 trisomy syndromes . Arch Otolaryngol 83:439-445, 1966.Crossref 6. Saito H, Okano Y, Furuta M, et al: Temporal bone findings in trisomy D . Arch Otolaryngol 100:386-389, 1974.Crossref 7. Kelemen G, Hooft C, Kluyskens P: The inner ear in autosomal trisomy . Pract Otorhinolaryngol 30:251-258, 1968. 8. Maniglia AJ, Wolff D, Herques AJ: Congenital deafness in 13-15 trisomy syndrome . Arch Otolaryngol 92:181-188, 1970.Crossref 9. Wright JL, Schuknecht HF: Atrophy of the spiral ligament . Arch Otolaryngol 96:16-21, 1972.Crossref 10. Schuknecht HF: Pathology of the Ear . Cambridge, Mass: Harvard University Press, 1974, chap 1 , pp 16-18.

Journal

Archives of OtolaryngologyAmerican Medical Association

Published: Jan 1, 1978

References