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Highlights

Highlights In This Issue January 2018 Volume 75, Number 1 JAMA Psychiatry Pages 1-108 Research Opinion Viewpoint Biomarkers for Glutamate-Targeted Drug Development 11 3 Addressing the Causality Gap in Human Drug development in psychotic disorders is hampered by a lack of functional target- Psychiatric Neuroscience engagement biomarkers. Javitt and colleagues evaluated ketamine-evoked changes in func- A Etkin tional magnetic resonance imaging blood oxygen level–dependent response, glutamate pro- Editorial ton magnetic spectroscopy, and task-based functional magnetic resonance imaging in brain 5 War-Related Traumas and Mental glutamate in 65 healthy volunteers across 3 sites and found a highly significant increase in Health Across Generations functional magnetic resonance imaging blood oxygen level–dependent response that was TS Betancourt and Coauthors consistent across sites. In an Invited Commentary, Kraguljac and Lahti discuss the implica- 7 Coherence Through Incongruence— tions of these findings for new drug development efforts. Can Genetic Markers Inform Nosology Invited Commentary 19 After All? L Wille and FJ McMahon Continuing Medical Education jamanetwork.com/learning 9 Putting Psychosis Into Sociocultural Context: An International Study War Evacuation and Hospitalization in Next Generation 21 in 17 Locations It is not known whether adverse childhood experiences are associated with worse mental E Susser and G Martínez-Alés health http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Psychiatry American Medical Association

Highlights

JAMA Psychiatry , Volume 75 (1) – Jan 1, 2018
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Highlights

Abstract

In This Issue January 2018 Volume 75, Number 1 JAMA Psychiatry Pages 1-108 Research Opinion Viewpoint Biomarkers for Glutamate-Targeted Drug Development 11 3 Addressing the Causality Gap in Human Drug development in psychotic disorders is hampered by a lack of functional target- Psychiatric Neuroscience engagement biomarkers. Javitt and colleagues evaluated ketamine-evoked changes in func- A Etkin tional magnetic resonance imaging blood oxygen level–dependent response, glutamate pro-...
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Publisher
American Medical Association
Copyright
Copyright 2018 American Medical Association. All Rights Reserved.
ISSN
2168-622X
eISSN
2168-6238
DOI
10.1001/jamapsychiatry.2017.1494
Publisher site
See Article on Publisher Site

Abstract

In This Issue January 2018 Volume 75, Number 1 JAMA Psychiatry Pages 1-108 Research Opinion Viewpoint Biomarkers for Glutamate-Targeted Drug Development 11 3 Addressing the Causality Gap in Human Drug development in psychotic disorders is hampered by a lack of functional target- Psychiatric Neuroscience engagement biomarkers. Javitt and colleagues evaluated ketamine-evoked changes in func- A Etkin tional magnetic resonance imaging blood oxygen level–dependent response, glutamate pro- Editorial ton magnetic spectroscopy, and task-based functional magnetic resonance imaging in brain 5 War-Related Traumas and Mental glutamate in 65 healthy volunteers across 3 sites and found a highly significant increase in Health Across Generations functional magnetic resonance imaging blood oxygen level–dependent response that was TS Betancourt and Coauthors consistent across sites. In an Invited Commentary, Kraguljac and Lahti discuss the implica- 7 Coherence Through Incongruence— tions of these findings for new drug development efforts. Can Genetic Markers Inform Nosology Invited Commentary 19 After All? L Wille and FJ McMahon Continuing Medical Education jamanetwork.com/learning 9 Putting Psychosis Into Sociocultural Context: An International Study War Evacuation and Hospitalization in Next Generation 21 in 17 Locations It is not known whether adverse childhood experiences are associated with worse mental E Susser and G Martínez-Alés health

Journal

JAMA Psychiatry – American Medical Association

Published: Jan 1, 2018

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