Abstract The purpose of this paper is to demonstrate the effects of high-energy electron therapy upon the clinical skin manifestations of a group of patients with atopic dermatitis, disseminated neurodermatitis, generalized exfoliative dermatitis, and psoriasis. MATERIAL AND METHODS A compressed gas insulated electrostatic accelerator of the Van de Graaff type produced the high-energy electrons or cathode rays. The High Voltage Research Laboratory at the Massachusetts Institute of Technology, Cambridge, Mass., made available its equipment and facilities for these studies. The electrons emerge from the tube extension of the Van de Graaff accelerator in a treatment room below the instrument. The electron stream finally passes through a narrow slit at the bottom of a cone, 1 meter long, and emerges as a downward directed ribbon of electrons through which the patient is passed (Figure). Trump and Van de Graaff* showed that the biologic effects of high-energy cathode rays and References 1. References 1 and 2. 2. Trump, J. G., and Van de Graaff, R. J.: Irradiation of Biological Materials by High Energy Roentgen Rays and Cathode Rays , J. Appl. Physics 19:599-604 ( (July) ) 1948.Crossref 3. Trump, J. G.; Van de Graaff, R. J., and Cloud, R. W.: Cathode Rays for Radiation Therapy , Am. J. Roentgenol. 43:728-734 ( (May) ) 1940. 4. Trump, J. G.; Wright, K. A.; Evans, W. W.; Anson, J. H.; Hare, H. F.; Fromer, J. L.; Jacque, G., and Horne, K. W.: High Energy Electrons for the Treatment of Extensive Superficial Malignancies , Am. J. Roentgenol. 69:623-629 ( (April) ) 1953.
A.M.A. Archives of Dermatology – American Medical Association
Published: Mar 1, 1955