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Herpes Zoster: Case Report of Possible Accidental Inoculation

Herpes Zoster: Case Report of Possible Accidental Inoculation Abstract • A 30-year-old healthy male physician developed grouped, papulovesicular lesions along the dermatomes of T1 and T2 of the left side of his body. The onset occurred two days after he accidentally pricked his right index finger with a needle that had been used to aspirate the acute papulovesicular lesions of a patient with severe herpes zoster. The clinical appearance and dermatomal distribution, the subsequent clinical course, the skin biopsy findings, and the substantial increase in complement-fixing antibody titer to the varicella-zoster (V-Z) virus in the convalescent serum samples are strong evidence for herpes zoster. Although it is generally believed that person-to-person transmission of zoster is rare and that herpes zoster results from the reactivation of a latent varicella virus, the present case suggests that zoster can be acquired from exogenous infection with a V-Z virus, at least in certain circumstances. (Arch Dermatol 112:1755-1756, 1976) References 1. Hope-Simpson RE: The nature of herpes zoster: A long-term study and a new hypothesis . Proc R Soc Med 58:9-20, 1965. 2. Kundratitz K: Experimentelle Übertragungen von Herpes zoster auf Menschen und die Beziehungen von Herpes zoster zu Varicellen . Z Kinderheilkd 39:379-387, 1925.Crossref 3. Miller LH, Brunell PA: Zoster, reinfection or activation of latent virus? Observation on the antibody response . Am J Med 49:480-483, 1970.Crossref 4. McKendrick GDW: Herpes zoster and varicella . Br Med J 3:587, 1970.Crossref 5. Rifkind D: The activation of varicella-zoster virus infections by immunosuppressive therapy . J Lab Clin Med 68:463-474, 1966. 6. Muller SA, Winkelmann RK: Cutaneous nerve changes in zoster . J Invest Dermatol 52:71-77, 1969. 7. Ghatak NR, Zimmerman HM: Spinal ganglion in herpes zoster: A light and electron microscopic study . Arch Pathol 95:411-415, 1973. 8. Berlin BS, Campbell T: Hospital-acquired herpes zoster following exposure to chickenpox . JAMA 211:1831-1833, 1970.Crossref 9. Rado JP, Tako J, Geder L, et al: Herpes zoster house epidemic in steroid-treated patients: A clinical and viral study . Arch Intern Med 116:329-335, 1965.Crossref 10. Goldberg LC: A clinical note on herpes zoster . Arch Dermatol 78:392-393, 1958Crossref 11. Thomas M: Shingles reconsidered . Lancet 2:47, 1964.Crossref 12. Thomas M, Robertson WJ: Dermal transmission of virus as a cause of shingles . Lancet 2:1349-1350, 1971.Crossref 13. Netter A, Ernoul J: Zona dans le territoire du médian gauche vingt-six jours après une légère piqûre à l'extrémité du médian gauche au cours d'une evisceration d'un globe oculaire atteint de fonte purulente de la cornée suite d'un zona ophtalmique . Bull Soc Med Hop Paris 50:798-800, 1934. 14. Feldman GV: Herpes zoster neonatorum . Arch Dis Child 27:126-127, 1952.Crossref 15. Herrmann EC Jr: Experiences in laboratory diagnosis of herpes simplex, varicella-zoster and vaccinia virus infections in routine medical practice . Mayo Clin Proc 42:744-753, 1967. 16. Muller SA: Recurrent herpes simplex of the hard palate: Case report and comment concerning reinfection and rarity of disease in the mouth . Arch Dermatol 98:273-276, 1968.Crossref 17. Muller SA, Herrmann EC Jr: Association of stomatitis and paronychias due to herpes simplex . Arch Dermatol 101:396-402, 1970.Crossref 18. Blank H, Haines HG: Experimental human reinfection with herpes simplex virus . J Invest Dermatol 61:223-225, 1973.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Herpes Zoster: Case Report of Possible Accidental Inoculation

Archives of Dermatology , Volume 112 (12) – Dec 1, 1976

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Publisher
American Medical Association
Copyright
Copyright © 1976 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1976.01630370043010
Publisher site
See Article on Publisher Site

Abstract

Abstract • A 30-year-old healthy male physician developed grouped, papulovesicular lesions along the dermatomes of T1 and T2 of the left side of his body. The onset occurred two days after he accidentally pricked his right index finger with a needle that had been used to aspirate the acute papulovesicular lesions of a patient with severe herpes zoster. The clinical appearance and dermatomal distribution, the subsequent clinical course, the skin biopsy findings, and the substantial increase in complement-fixing antibody titer to the varicella-zoster (V-Z) virus in the convalescent serum samples are strong evidence for herpes zoster. Although it is generally believed that person-to-person transmission of zoster is rare and that herpes zoster results from the reactivation of a latent varicella virus, the present case suggests that zoster can be acquired from exogenous infection with a V-Z virus, at least in certain circumstances. (Arch Dermatol 112:1755-1756, 1976) References 1. Hope-Simpson RE: The nature of herpes zoster: A long-term study and a new hypothesis . Proc R Soc Med 58:9-20, 1965. 2. Kundratitz K: Experimentelle Übertragungen von Herpes zoster auf Menschen und die Beziehungen von Herpes zoster zu Varicellen . Z Kinderheilkd 39:379-387, 1925.Crossref 3. Miller LH, Brunell PA: Zoster, reinfection or activation of latent virus? Observation on the antibody response . Am J Med 49:480-483, 1970.Crossref 4. McKendrick GDW: Herpes zoster and varicella . Br Med J 3:587, 1970.Crossref 5. Rifkind D: The activation of varicella-zoster virus infections by immunosuppressive therapy . J Lab Clin Med 68:463-474, 1966. 6. Muller SA, Winkelmann RK: Cutaneous nerve changes in zoster . J Invest Dermatol 52:71-77, 1969. 7. Ghatak NR, Zimmerman HM: Spinal ganglion in herpes zoster: A light and electron microscopic study . Arch Pathol 95:411-415, 1973. 8. Berlin BS, Campbell T: Hospital-acquired herpes zoster following exposure to chickenpox . JAMA 211:1831-1833, 1970.Crossref 9. Rado JP, Tako J, Geder L, et al: Herpes zoster house epidemic in steroid-treated patients: A clinical and viral study . Arch Intern Med 116:329-335, 1965.Crossref 10. Goldberg LC: A clinical note on herpes zoster . Arch Dermatol 78:392-393, 1958Crossref 11. Thomas M: Shingles reconsidered . Lancet 2:47, 1964.Crossref 12. Thomas M, Robertson WJ: Dermal transmission of virus as a cause of shingles . Lancet 2:1349-1350, 1971.Crossref 13. Netter A, Ernoul J: Zona dans le territoire du médian gauche vingt-six jours après une légère piqûre à l'extrémité du médian gauche au cours d'une evisceration d'un globe oculaire atteint de fonte purulente de la cornée suite d'un zona ophtalmique . Bull Soc Med Hop Paris 50:798-800, 1934. 14. Feldman GV: Herpes zoster neonatorum . Arch Dis Child 27:126-127, 1952.Crossref 15. Herrmann EC Jr: Experiences in laboratory diagnosis of herpes simplex, varicella-zoster and vaccinia virus infections in routine medical practice . Mayo Clin Proc 42:744-753, 1967. 16. Muller SA: Recurrent herpes simplex of the hard palate: Case report and comment concerning reinfection and rarity of disease in the mouth . Arch Dermatol 98:273-276, 1968.Crossref 17. Muller SA, Herrmann EC Jr: Association of stomatitis and paronychias due to herpes simplex . Arch Dermatol 101:396-402, 1970.Crossref 18. Blank H, Haines HG: Experimental human reinfection with herpes simplex virus . J Invest Dermatol 61:223-225, 1973.Crossref

Journal

Archives of DermatologyAmerican Medical Association

Published: Dec 1, 1976

References