Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

Hepatectomy for Early Hepatocellular Carcinoma

Hepatectomy for Early Hepatocellular Carcinoma Hepatectomy for Early Hepatocellular Carcinoma Invited Commentary Invited Commentary Not If, but When and How? Roberto Hernandez-Alejandro, MD; Mark A. Levstik, MD; David C. Linehan, MD Hepatocellular carcinoma (HCC) incidence is increasing glob- with resected HCC in NLs warrant close follow-up similar to ally despite recent advances in hepatitis C antiviral therapy and the LC/HCC resected group. is the third leading cause of cancer-related deaths worldwide. It is concerning that the authors did not address the phe- This has led to the development of a multidisciplinary approach nomenon that anatomic resections for HCC have a lower re- and enhanced treatment modalities involving interventional currence rate compared with nonanatomical resections. First, radiology, medical oncology, radiation oncology, hepatobiliary in this study, more than 60% of resections were nonanatomi- surgery, and transplantation. cal across groups. This surgical technique may play a role in In the current issue of JAMA Surgery, Sasaki et al report both higher NL recurrence rates and multiple sites of recur- the results of surgical resection for HCC for patients with liver rence. Second, more than a quarter of HCCs were less than 3.0 cirrhosis (LC) compared with a matched cohort of patients with cm. We are curious to http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Surgery American Medical Association

Hepatectomy for Early Hepatocellular Carcinoma

Download PDF
1 page
Read Article

Hepatectomy for Early Hepatocellular Carcinoma

Abstract

Hepatectomy for Early Hepatocellular Carcinoma Invited Commentary Invited Commentary Not If, but When and How? Roberto Hernandez-Alejandro, MD; Mark A. Levstik, MD; David C. Linehan, MD Hepatocellular carcinoma (HCC) incidence is increasing glob- with resected HCC in NLs warrant close follow-up similar to ally despite recent advances in hepatitis C antiviral therapy and the LC/HCC resected group. is the third leading cause of cancer-related deaths worldwide. It is concerning that the authors...
Loading next page...
 
/lp/american-medical-association/hepatectomy-for-early-hepatocellular-carcinoma-K50lC2xFNT
Publisher
American Medical Association
Copyright
Copyright 2017 American Medical Association. All Rights Reserved.
ISSN
2168-6254
eISSN
2168-6262
DOI
10.1001/jamasurg.2016.5042
pmid
28052157
Publisher site
See Article on Publisher Site

Abstract

Hepatectomy for Early Hepatocellular Carcinoma Invited Commentary Invited Commentary Not If, but When and How? Roberto Hernandez-Alejandro, MD; Mark A. Levstik, MD; David C. Linehan, MD Hepatocellular carcinoma (HCC) incidence is increasing glob- with resected HCC in NLs warrant close follow-up similar to ally despite recent advances in hepatitis C antiviral therapy and the LC/HCC resected group. is the third leading cause of cancer-related deaths worldwide. It is concerning that the authors did not address the phe- This has led to the development of a multidisciplinary approach nomenon that anatomic resections for HCC have a lower re- and enhanced treatment modalities involving interventional currence rate compared with nonanatomical resections. First, radiology, medical oncology, radiation oncology, hepatobiliary in this study, more than 60% of resections were nonanatomi- surgery, and transplantation. cal across groups. This surgical technique may play a role in In the current issue of JAMA Surgery, Sasaki et al report both higher NL recurrence rates and multiple sites of recur- the results of surgical resection for HCC for patients with liver rence. Second, more than a quarter of HCCs were less than 3.0 cirrhosis (LC) compared with a matched cohort of patients with cm. We are curious to

Journal

JAMA Surgery – American Medical Association

Published: Mar 4, 2017

References

  • The epidemiology of hepatocellular cancer: from the perspectives of public health problem to tumor biology
    Caldwell, S; Park, SH
  • Effect of background liver cirrhosis on outcomes of hepatectomy for hepatocellular carcinoma [published January 4, 2017]
    Sasaki, K; Shindoh, J; Margonis, GA
  • A snapshot of the effective indications and results of surgery for hepatocellular carcinoma in tertiary referral centers: is it adherent to the EASL/AASLD recommendations?: an observational study of the HCC East-West study group
    Torzilli, G; Belghiti, J; Kokudo, N
  • Resection of hepatocellular cancer ≤2 cm: results from two Western centers
    Roayaie, S; Obeidat, K; Sposito, C
  • Long-term effectiveness of radiofrequency ablation for solitary small hepatocellular carcinoma: a retrospective analysis of 363 patients
    Francica, G; Saviano, A; De Sio, I
  • Radiofrequency ablation compared to resection in early-stage hepatocellular carcinoma
    Tohme, S; Geller, DA; Cardinal, JS
  • Predicting survival after liver transplantation in patients with hepatocellular carcinoma beyond the Milan criteria: a retrospective, exploratory analysis
    Mazzaferro, V; Llovet, JM; Miceli, R
  • Total tumor volume and alpha-fetoprotein for selection of transplant candidates with hepatocellular carcinoma: a prospective validation
    Toso, C; Meeberg, G; Hernandez-Alejandro, R

You’re reading a free preview. Subscribe to read the entire article.

Try 2 weeks free now

DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

or browse the journals available

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$499/year

Save searches from
Google Scholar,
PubMed

Create folders to
organize your research

Export folders, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

Sign up
for free
Start 14 day
Free Trial