ARTICLE Chang-Hsien Yu, MD; Hung-Chi Lue, MD, PhD; Shye-Jao Wu, MD; Ming-Ren Chen, MD Objective: To evaluate the sensitivity of a heart dis- Main Outcome Measures: Previously unsuspected ease screening program for schoolchildren. heart diseases. Design: Prospective cohort study. Results: Of 25 816 children undergoing the level 1 screen- ing program, 5330 had positive findings, of whom 5235 Setting: Taitung County, Taiwan. underwent level 2 screening, along with 1104 children in the control group. The pediatric cardiologist referred 780 Participants: All first- and fourth-grade elementary childrentothehospitalforfullevaluation,including18con- school students and first-year junior high school stu- trols and 114 patients with a previous diagnosis of heart dents screened between September 1, 2005, and June disease. A total of 292 children, including 2 controls, had 30, 2007. evidenceofheartdisease,whichwaspreviouslyunsuspected in 178 (61.0%). Excluding children with a previous diag- Intervention: A 2-level heart disease screening pro- nosis of heart disease, the sensitivity of the screening pro- gram was undertaken. Level 1 screening included a his- gram was 82.6%. The specificity and the positive predictive tory questionnaire and phonocardiography and electro- value were 98.3% and 28.6%, respectively. cardiography. Level 2 screening consisted of examination by a pediatric cardiologist of all children who had ab- Conclusion:
JAMA Pediatrics – American Medical Association
Published: Mar 1, 2009
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