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HBV vaccine immunogenic in neonates

HBV vaccine immunogenic in neonates Evidence that immunization of infants with hepatitis B vaccine is effective was reported at the recent annual meeting of the American Gastroenterological Association in Washington, DC, by Cladd Stevens, MD, of the New York Blood Center, New York City. Stevens has studied more than 400 children in Eastern Transvaal, a region where infection with hepatitis B virus (HBV) is endemic. In Stevens' study, the children were divided into three approximately equal groups and given hepatitis B vaccine according to three different protocols. The first group received the first of three standard 10-μg childhood doses at 6 months of age; a second group began the series at 3 months of age; and the third group within one week of birth. After receiving three doses of the vaccine, more than 90% of the children responded with substantial amounts of hepatitis B antibody. These results allay the concern that infants may not respond http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

HBV vaccine immunogenic in neonates

JAMA , Volume 250 (1) – Jul 1, 1983

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Publisher
American Medical Association
Copyright
Copyright © 1983 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1983.03340010011004
Publisher site
See Article on Publisher Site

Abstract

Evidence that immunization of infants with hepatitis B vaccine is effective was reported at the recent annual meeting of the American Gastroenterological Association in Washington, DC, by Cladd Stevens, MD, of the New York Blood Center, New York City. Stevens has studied more than 400 children in Eastern Transvaal, a region where infection with hepatitis B virus (HBV) is endemic. In Stevens' study, the children were divided into three approximately equal groups and given hepatitis B vaccine according to three different protocols. The first group received the first of three standard 10-μg childhood doses at 6 months of age; a second group began the series at 3 months of age; and the third group within one week of birth. After receiving three doses of the vaccine, more than 90% of the children responded with substantial amounts of hepatitis B antibody. These results allay the concern that infants may not respond

Journal

JAMAAmerican Medical Association

Published: Jul 1, 1983

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