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Hürthle Cell Neoplasms: Malignant Potential

Hürthle Cell Neoplasms: Malignant Potential Abstract • We studied the records of patients with Hürthle cell neoplasms seen at the University of California at San Francisco, from 1943 to 1982, because of controversy concerning the malignant potential of these tumors. Of our 84 patients, 71 had Hürthle cell adenomas (HCAs), nine had Hürthle cell change in chronic thyroiditis, and four had Hürthle cell carcinomas. Coexisting papillary thyroid carcinoma occurred in three patients with HCA. Twelve patients with HCAs had multiple lesions, five of which were bilateral. Patients with HCA were followed up for 675 patient-years, 45 for four years or more (maximum duration, 36 years). There were no recurrences or deaths among the patients with benign Hürthle cell tumors. Thus, patients with HCA had a benign course, and histologic examination results accurately reflected malignant potential. (Arch Surg 1984;119:515-519) References 1. Gundry SR, Burney RE, Thompson NW, et al: Total thyroidectomy for Hürthle cell neoplasms of the thyroid . Arch Surg 1983;118:529-532.Crossref 2. Thompson NW, Dunn EL, Batsakis JG, et al: Hürthle cell lesions of the thyroid gland . Surg Gynecol Obstet 1974;139:555-560. 3. Bondeson L, Bondeson AG, Ljungberg D, et al: Oxyphil tumors of the thyroid: Follow-up of 42 surgical cases . Ann Surg 1981;196:677-680.Crossref 4. Tollefson HR, Shah JP, Huvos AG: Hürthle cell carcinoma of the thyroid . Am J Surg 1975;130:390-394.Crossref 5. Brennan MP, Watson RG, Goellner JR, et al: Survival and death from Hürthle cell cancer, abstract T68. Program and abstracts of the 59th meeting of the American Thyroid Association, New Orleans, Oct 5-8, 1983. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

Hürthle Cell Neoplasms: Malignant Potential

Archives of Surgery , Volume 119 (5) – May 1, 1984

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Publisher
American Medical Association
Copyright
Copyright © 1984 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1984.01390170015004
Publisher site
See Article on Publisher Site

Abstract

Abstract • We studied the records of patients with Hürthle cell neoplasms seen at the University of California at San Francisco, from 1943 to 1982, because of controversy concerning the malignant potential of these tumors. Of our 84 patients, 71 had Hürthle cell adenomas (HCAs), nine had Hürthle cell change in chronic thyroiditis, and four had Hürthle cell carcinomas. Coexisting papillary thyroid carcinoma occurred in three patients with HCA. Twelve patients with HCAs had multiple lesions, five of which were bilateral. Patients with HCA were followed up for 675 patient-years, 45 for four years or more (maximum duration, 36 years). There were no recurrences or deaths among the patients with benign Hürthle cell tumors. Thus, patients with HCA had a benign course, and histologic examination results accurately reflected malignant potential. (Arch Surg 1984;119:515-519) References 1. Gundry SR, Burney RE, Thompson NW, et al: Total thyroidectomy for Hürthle cell neoplasms of the thyroid . Arch Surg 1983;118:529-532.Crossref 2. Thompson NW, Dunn EL, Batsakis JG, et al: Hürthle cell lesions of the thyroid gland . Surg Gynecol Obstet 1974;139:555-560. 3. Bondeson L, Bondeson AG, Ljungberg D, et al: Oxyphil tumors of the thyroid: Follow-up of 42 surgical cases . Ann Surg 1981;196:677-680.Crossref 4. Tollefson HR, Shah JP, Huvos AG: Hürthle cell carcinoma of the thyroid . Am J Surg 1975;130:390-394.Crossref 5. Brennan MP, Watson RG, Goellner JR, et al: Survival and death from Hürthle cell cancer, abstract T68. Program and abstracts of the 59th meeting of the American Thyroid Association, New Orleans, Oct 5-8, 1983.

Journal

Archives of SurgeryAmerican Medical Association

Published: May 1, 1984

References