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Griseofulvin-Containing Medium for Simplified Diagnosis of Dermatophytosis

Griseofulvin-Containing Medium for Simplified Diagnosis of Dermatophytosis Abstract By inoculating paired tubes of standard Sabouraud dextrose-chloramphenicol-cycloheximide media, one of which contained in addition 20μg/ml of griseofulvin, 86 of 88 griseofulvin-sensitive dermatophytes were recognized in 226 primary isolation cultures. Most yeast, bacteria, and mold contaminants were not selectively inhibited by the media. The method facilitates the selection of patients for oral griseofulvin therapy by those with relatively little training in mycology. References 1. Georg, L.K.; Ajello, L.; and Papageorge, C.: Use of Cycloheximide in the Selective Isolation of Fungi Pathogenic to Man , J Lab Clin Med 44:422, 1954. 2. Hildick-Smith, G.; Blank, H.; and Sarkany, L.: Fungus Diseases and Their Treatment , Boston: Little, Brown and Co., 1964. 3. McDonough, E.S., et al: Growth of Dimorphic Human Pathogenic Fungi on Media Containing Cycloheximide and Chloramphenicol , Mycopathologia 13:113, 1960. 4. Rebell, G.; Taplin, D.; and Blank, H.: Dermatophytes: Their Recognition and Identification , Miami, Fla: Dermatological Foundation, 1964. 5. Sandhu, R.S., and Randhawa, H.S.: Action of Griseofulvin on Geophilic Dermatophytes and Related Keratinophilic Fungi , Mycopathologia 22:141, 1964. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Griseofulvin-Containing Medium for Simplified Diagnosis of Dermatophytosis

Archives of Dermatology , Volume 92 (3) – Sep 1, 1965

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Publisher
American Medical Association
Copyright
Copyright © 1965 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1965.01600150109021
Publisher site
See Article on Publisher Site

Abstract

Abstract By inoculating paired tubes of standard Sabouraud dextrose-chloramphenicol-cycloheximide media, one of which contained in addition 20μg/ml of griseofulvin, 86 of 88 griseofulvin-sensitive dermatophytes were recognized in 226 primary isolation cultures. Most yeast, bacteria, and mold contaminants were not selectively inhibited by the media. The method facilitates the selection of patients for oral griseofulvin therapy by those with relatively little training in mycology. References 1. Georg, L.K.; Ajello, L.; and Papageorge, C.: Use of Cycloheximide in the Selective Isolation of Fungi Pathogenic to Man , J Lab Clin Med 44:422, 1954. 2. Hildick-Smith, G.; Blank, H.; and Sarkany, L.: Fungus Diseases and Their Treatment , Boston: Little, Brown and Co., 1964. 3. McDonough, E.S., et al: Growth of Dimorphic Human Pathogenic Fungi on Media Containing Cycloheximide and Chloramphenicol , Mycopathologia 13:113, 1960. 4. Rebell, G.; Taplin, D.; and Blank, H.: Dermatophytes: Their Recognition and Identification , Miami, Fla: Dermatological Foundation, 1964. 5. Sandhu, R.S., and Randhawa, H.S.: Action of Griseofulvin on Geophilic Dermatophytes and Related Keratinophilic Fungi , Mycopathologia 22:141, 1964.

Journal

Archives of DermatologyAmerican Medical Association

Published: Sep 1, 1965

References