EDITORIAL Room for Improvement in Both Performance and Measurement LAUCOMA IS THE LEADING CAUSE OF IR- a sample medication as prescribed but never filled the 1,2 reversible blindness worldwide and the prescription for the medication when the sample ran out number of Americans with glaucoma is would be nonpersistent. Previously, the term compli- expected to increase by 50% in the next ance was often used to describe how well a patient fol- G 15 years. Multiple clinical trials have lowed physician instructions. The terms adherence and shown that with effective medical treatment, much (but persistence have largely replaced compliance as more spe- 4-6 not all) vision loss can be prevented. Whether mea- cific terms for describing the often complex relation- 7 8,9 sured by pharmacy data, self-report, or medication ship between prescribed and actual medication use. monitor, adherence to glaucoma medication is often poor. Investigators studying medication adherence have COMPONENTS OF MEDICATION ADHERENCE identified multiple factors related to poor adherence, in- 11 12 cluding more frequent and complex dosing and situ- Once a patient accepts that medical therapy is indi- ational factors, such as competing activities and for- cated, proper adherence to a prescribed glaucoma medi- getfulness, as well
JAMA Ophthalmology – American Medical Association
Published: Feb 1, 2011
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