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Generalized Pustular Psoriasis Provoked by Propranolol

Generalized Pustular Psoriasis Provoked by Propranolol Abstract • An 80-year-old man who had had plaque-type psoriasis for 40 years experienced a rapid onset of generalized pustular psoriasis three days after initiation of propranolol hydrochloride therapy. Trial therapy with propranolol on two occasions resulted in similar episodes. The skin lesions and systemic symptoms resolved after the discontinuation of propranolol therapy and administration of methotrexate sodium. This case study documents propranolol—a β-blocker—as another causal factor for pustular psoriasis. (Arch Dermatol 1985;121:1326-1327) References 1. Shelley WB: Birch pollen and aspirin psoriasis: A study in salicylate hypersensitivity . JAMA 1964;189:985-988. 2. Murphy FR, Stolman LP: Generalized pustular psoriasis . Arch Dermatol 1979;115:1215-1216.Crossref 3. Shelley WB: Generalized pustular psoriasis induced by potassium iodide . JAMA 1967;201:1009-1014.Crossref 4. Reshad H, Hargreaves GK, Vickers CFH: Generalized pustular psoriasis precipitated by phenylbutazone and oxyphenbutazone . Br J Dermatol 1983;109:111-113.Crossref 5. Ogawa M, Baughman RD, Clendenning WE: Generalized pustular psoriasis: Induction by topical use of coal tar . Arch Dermatol 1969;99:671-673.Crossref 6. Baker H, Ryan TJ: Generalized pustular psoriasis: A clinical and epidemiological study of 104 cases . Br J Dermatol 1968;80:771-792.Crossref 7. Petrozzi JW, Witkowski JA: Acrodermatitis perstans: Generalization following therapy with nystatin . Arch Dermatol 1971;103:442-447.Crossref 8. Lowe NJ, Ridgway HB: Generalized pustular psoriasis precipitated by lithium carbonate . Arch Dermatol 1978;114:1788-1789.Crossref 9. White SW: Palmoplantar pustular psoriasis provoked by lithium therapy . J Am Acad Dermatol 1982;7:660-662.Crossref 10. Felix RH, Ive FA, Dahl MGC: Cutaneous and ocular reactions to practolol . Br Med J 1974;4:321-324.Crossref 11. Jensen HE, Mikkelsen HI, Wadskov S, et al: Cutaneous reactions to propranolol (Inderal) . Acta Med Scand 1976;199:363-367.Crossref 12. Halevy S, Feuerman EJ: Psoriasiform eruption induced by propranolol . Cutis 1979;24:95-98. 13. Cochran REI, Thomson J, McQueen A, et al: Skin reactions associated with propranolol . Arch Dermatol 1976;112:1173-1174.Crossref 14. Hawk JLM: Lichenoid drug eruption induced by propranolol . Clin Exp Dermatol 1980;5:93-96.Crossref 15. Gaylarde PM, Brock AP, Sarkany I: Psoriasiform changes in guinea-pig skin from propranolol . Clin Exp Dermatol 1978;3:157-160.Crossref 16. Powell JA, Duell EA, Voorhees JJ: Beta adrenergic stimulation of endogenous epidermal cyclic AMP formation . Arch Dermatol 1971;104:359-365.Crossref 17. Duell EA, Voorhees JJ, Kelsey WH, et al: Isoproterenolsensitive adenylcyclase in a particulate fraction of epidermis . Arch Dermatol 1971;104:601-610.Crossref 18. Claesson H-E, Lundberg U, Malmsten C: Serum-coated zymosan stimulates the synthesis of leukotriene B4 in human polymorphonuclear leukocytes: Inhibition by cyclic AMP . Biochem Biophys Res Commun 1981;99:1230-1237.Crossref 19. Ignarro LJ: Cyclic nucleotides and lysosomal enzyme secretion , in Cramer H, Schultz J (eds): Cyclic, 3',5′-Nucleotides: Mechanisms of Action . New York, John Wiley & Sons Inc, 1977, pp 189-206. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Generalized Pustular Psoriasis Provoked by Propranolol

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Publisher
American Medical Association
Copyright
Copyright © 1985 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1985.01660100106027
Publisher site
See Article on Publisher Site

Abstract

Abstract • An 80-year-old man who had had plaque-type psoriasis for 40 years experienced a rapid onset of generalized pustular psoriasis three days after initiation of propranolol hydrochloride therapy. Trial therapy with propranolol on two occasions resulted in similar episodes. The skin lesions and systemic symptoms resolved after the discontinuation of propranolol therapy and administration of methotrexate sodium. This case study documents propranolol—a β-blocker—as another causal factor for pustular psoriasis. (Arch Dermatol 1985;121:1326-1327) References 1. Shelley WB: Birch pollen and aspirin psoriasis: A study in salicylate hypersensitivity . JAMA 1964;189:985-988. 2. Murphy FR, Stolman LP: Generalized pustular psoriasis . Arch Dermatol 1979;115:1215-1216.Crossref 3. Shelley WB: Generalized pustular psoriasis induced by potassium iodide . JAMA 1967;201:1009-1014.Crossref 4. Reshad H, Hargreaves GK, Vickers CFH: Generalized pustular psoriasis precipitated by phenylbutazone and oxyphenbutazone . Br J Dermatol 1983;109:111-113.Crossref 5. Ogawa M, Baughman RD, Clendenning WE: Generalized pustular psoriasis: Induction by topical use of coal tar . Arch Dermatol 1969;99:671-673.Crossref 6. Baker H, Ryan TJ: Generalized pustular psoriasis: A clinical and epidemiological study of 104 cases . Br J Dermatol 1968;80:771-792.Crossref 7. Petrozzi JW, Witkowski JA: Acrodermatitis perstans: Generalization following therapy with nystatin . Arch Dermatol 1971;103:442-447.Crossref 8. Lowe NJ, Ridgway HB: Generalized pustular psoriasis precipitated by lithium carbonate . Arch Dermatol 1978;114:1788-1789.Crossref 9. White SW: Palmoplantar pustular psoriasis provoked by lithium therapy . J Am Acad Dermatol 1982;7:660-662.Crossref 10. Felix RH, Ive FA, Dahl MGC: Cutaneous and ocular reactions to practolol . Br Med J 1974;4:321-324.Crossref 11. Jensen HE, Mikkelsen HI, Wadskov S, et al: Cutaneous reactions to propranolol (Inderal) . Acta Med Scand 1976;199:363-367.Crossref 12. Halevy S, Feuerman EJ: Psoriasiform eruption induced by propranolol . Cutis 1979;24:95-98. 13. Cochran REI, Thomson J, McQueen A, et al: Skin reactions associated with propranolol . Arch Dermatol 1976;112:1173-1174.Crossref 14. Hawk JLM: Lichenoid drug eruption induced by propranolol . Clin Exp Dermatol 1980;5:93-96.Crossref 15. Gaylarde PM, Brock AP, Sarkany I: Psoriasiform changes in guinea-pig skin from propranolol . Clin Exp Dermatol 1978;3:157-160.Crossref 16. Powell JA, Duell EA, Voorhees JJ: Beta adrenergic stimulation of endogenous epidermal cyclic AMP formation . Arch Dermatol 1971;104:359-365.Crossref 17. Duell EA, Voorhees JJ, Kelsey WH, et al: Isoproterenolsensitive adenylcyclase in a particulate fraction of epidermis . Arch Dermatol 1971;104:601-610.Crossref 18. Claesson H-E, Lundberg U, Malmsten C: Serum-coated zymosan stimulates the synthesis of leukotriene B4 in human polymorphonuclear leukocytes: Inhibition by cyclic AMP . Biochem Biophys Res Commun 1981;99:1230-1237.Crossref 19. Ignarro LJ: Cyclic nucleotides and lysosomal enzyme secretion , in Cramer H, Schultz J (eds): Cyclic, 3',5′-Nucleotides: Mechanisms of Action . New York, John Wiley & Sons Inc, 1977, pp 189-206.

Journal

Archives of DermatologyAmerican Medical Association

Published: Oct 1, 1985

References