Abstract • A keratoplasty was performed on the right eye of a 12-year-old boy affected by gelatinous drop-like corneal dystrophy. This rare form of primary corneal amyloidosis has been more often reported in Japanese than in occidental literature. In the case presented here, the occasional fusiform deposits of amyloid observed in the stroma suggest a relationship between gelatinous drop-like corneal dystrophy and lattice dystrophy. A new classification of the different types of primary corneal amyloidosis is proposed. References 1. Glenner GG, Page DL: Amyloid, amyloidosis, and amyloidogenesis , in Richter GW, Epstein MA (eds): International Review of Experimental Pathology . New York, Academic Press Inc, 1976, vol 15, pp 1-92. 2. Seitelberger F, Nemetz UR: Beitrag zur Frage der gittrigen Hornhautdystrophie . Albrecht Von Graefes Arch Klin Exp Ophthalmol 164:102-111, 1961.Crossref 3. Klintworth GK: Lattice corneal dystrophy: An inherited variety of amyloidosis restricted to the cornea . Am J Pathol 50:371-399, 1967. 4. Brownstein MH, Elliott R, Helwig EB: Ophthalmologic aspects of amyloidosis . Am J Ophthalmol 69:423-430, 1970. 5. Meretoja J: Familial systemic paramyloidosis with lattice dystrophy of the cornea, progressive cranial neuropathy, skin changes, and various internal symptoms: A previously unrecognized heritable syndrome . Ann Clin Res 1:314-324, 1969. 6. Nagataki S, Tanishima T, Sakomoto T: A case of primary gelatinous drop-like corneal dystrophy . Jpn J Ophthalmol 16:107-116, 1972. 7. Matsui M, Ito K, Akiya S: Histochemical and electron microscopic examinations on so-called gelatinous drop-like dystrophy of the cornea . Folia Ophthalmol 23:466-479, 1972. 8. Akiya S, Ito K, Matsui M: Gelatinous drop-like dystrophy of the cornea: Light and electron microscopic study of superficial stromal lesion . Jpn J Clin Ophthalmol 26:815-826, 1972. 9. Lewkojewa EF: Ueber einen Fall primärer Degenerationamyloidose der Kornea . Klin Monatsbl Augenheilkd 85( (suppl) ):117-145, 1930. 10. Kirk HQ, Rabb M, Hattenhauer J, et al: Primary familial amyloidosis of the cornea . Trans Am Acad Ophthalmol Otolaryngol 77:411-417, 1973. 11. Stock EL, Kielar RA: Primary familial amyloidosis of the cornea . Am J Ophthalmol 82:266-271, 1976. 12. McPherson SD Jr, Kiffney GT Jr, Freed CC: Corneal amyloidosis . Am J Ophthalmol 62:1025-1033, 1966. 13. Ramsey MS, Fine BS, Cohen SW: Localized corneal amyloidosis: Case report with electron microscopical examination . Am J Ophthalmol 73:560-565, 1972. 14. Meretoja J: Comparative histopathological and clinical findings in eyes with lattice corneal dystrophy of two different types . Ophthalmologica 165:15-37, 1972.Crossref 15. Meretoja J: Genetic aspect of familial amyloidosis with corneal lattice dystrophy . Clin Genet 4:173-185, 1973.Crossref 16. Leuenberger PM, Gnädinger MC, Cabernard E: Zur Frage der Kollagensynthese durch corneales Epithel: I. Elektronenmikroskopische Studie an regenerierten Epithel der Kaninchenhornhaut . Albrecht Von Graefes Arch Klin Exp Ophthalmol 187:171-182, 1973.Crossref 17. Garner A: Amyloidosis of the cornea . Br J Ophthalmol 53:73-81, 1969.Crossref 18. Francois J, Hanssens M, Teuchy H: Ultrastructural changes in lattice dystrophy of the cornea . Ophthalmic Res 7:321-344, 1975.Crossref 19. Babel J: Les alterations du collagène dans les dégénérescences cornéennes . Arch Ophthalmol 35:39-48, 1975. 20. Stafford WR, Fine BS: Amyloidosis of the cornea: Report of a case without conjunctival involvement . Arch Ophthalmol 75:53-56, 1966.Crossref 21. Pouliquen Y, Dhermy P, Taillebourg O: Etude au microscope électronique d'une dystrophie grillagée de Haab-Dimmer . Arch Ophthalmol 33:385-499, 1973. 22. Yanoff M, Fine BS, Colosi NJ, et al: Lattice corneal dystrophy: Report of an unusual case . Arch Ophthalmol 95:651-655, 1977.Crossref 23. Hogan MJ, Alvarado JA, Weddell JE: Histology of the Human Eye: An Atlas and Textbook . Philadelphia, WB Saunders Co, 1971, pp 52-111. 24. Witschel H, Sundmacher R: Bilateral recurrence of granular corneal dystrophy in the grafts . Albrecht Von Graefes Arch Klin Exp Ophthalmol 209:179-188, 1979.Crossref 25. Wobmann P, Epinay SL d': Die Ultrastruktur der gittrigen Hornhautdystrophie . Albrecht Von Graefes Arch Klin Ophthalmol 190:145-153, 1974.Crossref 26. Brownstein S, Fine BS, Sherman ME, et al: Granular dystrophy of the cornea: Light and electron microscopic confirmation of recurrence in a graft . Am J Ophthalmol 77:701-710, 1974. 27. Garner A: Histochemistry of corneal granular dystrophy . Br J Ophthalmol 53:799-807, 1969.Crossref
Archives of Ophthalmology – American Medical Association
Published: Jan 1, 1980
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