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Further Actions Are Needed to Prevent Maternal Deaths From Epilepsy

Further Actions Are Needed to Prevent Maternal Deaths From Epilepsy Letters thus believe that our study was well-poised to detect these Further Actions Are Needed to Prevent Maternal clinical manifestations of CTE, assuming that (1) CTE is asso- Deaths From Epilepsy ciated with these particular symptoms and (2) CTE was To the Editor We read with interest the article by Razaz et al present in a significant proportion of the football players in that documented the increased risks of a range of pregnancy our study. However, if the head trauma experienced by these complications in women with epilepsy. Reassuringly, there participants produced a different clinical profile that was was no additional increased risk associated with antiepilep- perhaps characterized by disinhibition and abulia, as sug- tic drug therapy. However, this large study did not have the gested by Hoffmann, we agree that the available measures power to examine the severest of maternal outcomes, would not be discriminating. maternal mortality. Hoffmann cites a recent study that suggests that “neuro- The United Kingdom’s confidential enquiry into mater- pathological data were discerning, with CTE diagnosed in 99% nal mortality showed that epilepsy was the leading cause of of National Football League Players.” This statement is mislead- death due to neurological causes among pregnant http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Neurology American Medical Association

Further Actions Are Needed to Prevent Maternal Deaths From Epilepsy

JAMA Neurology , Volume 75 (1) – Jan 4, 2018

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Publisher
American Medical Association
Copyright
Copyright 2017 American Medical Association. All Rights Reserved.
ISSN
2168-6149
eISSN
2168-6157
DOI
10.1001/jamaneurol.2017.3621
Publisher site
See Article on Publisher Site

Abstract

Letters thus believe that our study was well-poised to detect these Further Actions Are Needed to Prevent Maternal clinical manifestations of CTE, assuming that (1) CTE is asso- Deaths From Epilepsy ciated with these particular symptoms and (2) CTE was To the Editor We read with interest the article by Razaz et al present in a significant proportion of the football players in that documented the increased risks of a range of pregnancy our study. However, if the head trauma experienced by these complications in women with epilepsy. Reassuringly, there participants produced a different clinical profile that was was no additional increased risk associated with antiepilep- perhaps characterized by disinhibition and abulia, as sug- tic drug therapy. However, this large study did not have the gested by Hoffmann, we agree that the available measures power to examine the severest of maternal outcomes, would not be discriminating. maternal mortality. Hoffmann cites a recent study that suggests that “neuro- The United Kingdom’s confidential enquiry into mater- pathological data were discerning, with CTE diagnosed in 99% nal mortality showed that epilepsy was the leading cause of of National Football League Players.” This statement is mislead- death due to neurological causes among pregnant

Journal

JAMA NeurologyAmerican Medical Association

Published: Jan 4, 2018

References