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Fundus Autofluorescence in Autosomal Dominant Occult Macular Dystrophy

Fundus Autofluorescence in Autosomal Dominant Occult Macular Dystrophy CLINICAL SCIENCES Fundus Autofluorescence in Autosomal Dominant Occult Macular Dystrophy Kaoru Fujinami, MD; Kazushige Tsunoda, MD, PhD; Gen Hanazono, MD; Kei Shinoda, MD, PhD; Hisao Ohde, MD, PhD; Yozo Miyake, MD, PhD Objective: To characterize fundus autofluorescence fovea bilaterally. The optical coherence tomographic im- (FAF) images of eyes with autosomal dominant occult ages showed abnormalities of the photoreceptor inner seg- macular dystrophy (OMD). ment–outer segment line and cone outer segment tip line in all patients. However, 5 patients had normal FAF im- Methods: All patients received a comprehensive oph- ages regardless of morphological abnormalities of the pho- thalmologic examination for diagnosis of OMD. We evalu- toreceptor. ated the FAF images in 13 eyes of 7 patients with auto- somal dominant OMD by confocal scanning laser Conclusions: Fundus autofluorescence is a useful method ophthalmoscopy with excitation at 488 nm and emis- to acquire additional information of photoreceptor/ sion more than 500 nm. retinal pigment epithelium function in eyes with OMD. Fundus autofluorescence will be also helpful for the dif- Results: The FAF images showed unspecific weak fo- ferential diagnosis of eyes with OMD vs eyes with other veal hyperfluorescence in 4 eyes of 2 patients; one showed dystrophies that have http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Ophthalmology American Medical Association

Fundus Autofluorescence in Autosomal Dominant Occult Macular Dystrophy

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Publisher
American Medical Association
Copyright
Copyright 2011 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6165
eISSN
2168-6173
DOI
10.1001/archophthalmol.2011.96
pmid
21555613
Publisher site
See Article on Publisher Site

Abstract

CLINICAL SCIENCES Fundus Autofluorescence in Autosomal Dominant Occult Macular Dystrophy Kaoru Fujinami, MD; Kazushige Tsunoda, MD, PhD; Gen Hanazono, MD; Kei Shinoda, MD, PhD; Hisao Ohde, MD, PhD; Yozo Miyake, MD, PhD Objective: To characterize fundus autofluorescence fovea bilaterally. The optical coherence tomographic im- (FAF) images of eyes with autosomal dominant occult ages showed abnormalities of the photoreceptor inner seg- macular dystrophy (OMD). ment–outer segment line and cone outer segment tip line in all patients. However, 5 patients had normal FAF im- Methods: All patients received a comprehensive oph- ages regardless of morphological abnormalities of the pho- thalmologic examination for diagnosis of OMD. We evalu- toreceptor. ated the FAF images in 13 eyes of 7 patients with auto- somal dominant OMD by confocal scanning laser Conclusions: Fundus autofluorescence is a useful method ophthalmoscopy with excitation at 488 nm and emis- to acquire additional information of photoreceptor/ sion more than 500 nm. retinal pigment epithelium function in eyes with OMD. Fundus autofluorescence will be also helpful for the dif- Results: The FAF images showed unspecific weak fo- ferential diagnosis of eyes with OMD vs eyes with other veal hyperfluorescence in 4 eyes of 2 patients; one showed dystrophies that have

Journal

JAMA OphthalmologyAmerican Medical Association

Published: May 1, 2011

References

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