Fulminant Neonatal Meningococcemia
Clegg, Herbert W.;Todres, I. David;Moylan, Fergus M. B.;Keim, Daniel E.;Shannon, Daniel C.
1980-04-01 00:00:00
Abstract • Neisseria meningitidis is a rare cause of infection in infants younger than 2 months of age, presumably because of transplacental passage of protective maternal antibodies. In most reported cases of meningococcal disease in neonates, a relatively mild clinical course has been observed. A 25-day-old infant survived acute, severe meningococcemia due to group B N meningitidis. This organism should be considered when neonates have signs of septicemia, especially in the presence of cutaneous petechiae and purpura. (Am J Dis Child 134:354-355, 1980) References 1. Klein JO, Marcy SM: Bacterial infections , in Remington JS, Klein JO (eds): Infectious Diseases of the Fetus and Newborn Infant . Philadelphia, WB Saunders Co, 1976, p 747. 2. Groover RV, Sutherland JM, Landing BH: Purulent meningitis of newborn infants: Elevenyear experience in the antibiotic era . N Engl J Med 264:1115-1121, 1961.Crossref 3. Stiehm ER, Damrosch DS: Factors in the prognosis of meningococcal infection: Review of 63 cases with emphasis on recognition and management of the severely ill patient . J Pediatr 68:457-467, 1966.Crossref 4. Hodes HL: Endotoxin shock , in Smith CA (ed): The Critically Ill Child , ed 2. Philadelphia, WB Saunders Co, 1977, pp 25-45. 5. Gross S, Melhorn DK: Exchange transfusion with citrated whole blood for disseminated intravascular coagulation . J Pediatr 78:415-419, 1971.Crossref 6. Mauger DC: Hypokalemia as a consistent feature of fulminant meningococcal septicaemia . Aust Paediatr J 7:84-86, 1971. 7. Stiehm ER, Damrosch DS: Neonatal meningococcal meningitis: Report of a case acquired in the nursery . J Pediatr 68:654-656, 1966.Crossref 8. Sunderland WA, Harris HH, Spence DA, et al: Meningococcemia in a newborn infant whose mother had meningococcal vaginitis . J Pediatr 81:856, 1972.Crossref 9. Jones RN, Slepack J, Eades A: Fatal neonatal meningococcal meningitis: Association with maternal cervical-vaginal colonization . JAMA 236:2652-2653, 1976.Crossref 10. Goldschneider I, Gotschlich EC, Artenstein MS: Human immunity to the meningococcus: I. The role of humoral antibodies . J Exp Med 129:1307-1326, 1969.Crossref 11. Goldschneider I, Gotschlich EC, Artenstein MS: Human immunity to the meningococcus: II. Development of natural immunity . J Exp Med 129:1327-1348, 1969.Crossref 12. Carvalho AD, Giampaglia CM, Kimura H, et al: Maternal and infant antibody response to meningococcal vaccination in pregnancy . Lancet 2:809-811, 1977.Crossref 13. Faur YC, Weisburd MH, Wilson MD: Isolation of Neisseria meningitidis from the genitourinary tract and anal canal . J Clin Microbiol 2:178-182, 1975. 14. Judson FN, Ehret JM, Eickhoff TC: Anogenital infection with Neisseria meningitidis in homosexual men . J Infect Dis 137:458-463, 1978.Crossref 15. Manginello FP, Pascale JA, Wolfsdorf J: Neonatal meningococcemia . AJDC 133:651-652, 1979.
http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.pngAmerican Journal of Diseases of ChildrenAmerican Medical Associationhttp://www.deepdyve.com/lp/american-medical-association/fulminant-neonatal-meningococcemia-wJGGRwgzkO
Abstract • Neisseria meningitidis is a rare cause of infection in infants younger than 2 months of age, presumably because of transplacental passage of protective maternal antibodies. In most reported cases of meningococcal disease in neonates, a relatively mild clinical course has been observed. A 25-day-old infant survived acute, severe meningococcemia due to group B N meningitidis. This organism should be considered when neonates have signs of septicemia, especially in the presence of cutaneous petechiae and purpura. (Am J Dis Child 134:354-355, 1980) References 1. Klein JO, Marcy SM: Bacterial infections , in Remington JS, Klein JO (eds): Infectious Diseases of the Fetus and Newborn Infant . Philadelphia, WB Saunders Co, 1976, p 747. 2. Groover RV, Sutherland JM, Landing BH: Purulent meningitis of newborn infants: Elevenyear experience in the antibiotic era . N Engl J Med 264:1115-1121, 1961.Crossref 3. Stiehm ER, Damrosch DS: Factors in the prognosis of meningococcal infection: Review of 63 cases with emphasis on recognition and management of the severely ill patient . J Pediatr 68:457-467, 1966.Crossref 4. Hodes HL: Endotoxin shock , in Smith CA (ed): The Critically Ill Child , ed 2. Philadelphia, WB Saunders Co, 1977, pp 25-45. 5. Gross S, Melhorn DK: Exchange transfusion with citrated whole blood for disseminated intravascular coagulation . J Pediatr 78:415-419, 1971.Crossref 6. Mauger DC: Hypokalemia as a consistent feature of fulminant meningococcal septicaemia . Aust Paediatr J 7:84-86, 1971. 7. Stiehm ER, Damrosch DS: Neonatal meningococcal meningitis: Report of a case acquired in the nursery . J Pediatr 68:654-656, 1966.Crossref 8. Sunderland WA, Harris HH, Spence DA, et al: Meningococcemia in a newborn infant whose mother had meningococcal vaginitis . J Pediatr 81:856, 1972.Crossref 9. Jones RN, Slepack J, Eades A: Fatal neonatal meningococcal meningitis: Association with maternal cervical-vaginal colonization . JAMA 236:2652-2653, 1976.Crossref 10. Goldschneider I, Gotschlich EC, Artenstein MS: Human immunity to the meningococcus: I. The role of humoral antibodies . J Exp Med 129:1307-1326, 1969.Crossref 11. Goldschneider I, Gotschlich EC, Artenstein MS: Human immunity to the meningococcus: II. Development of natural immunity . J Exp Med 129:1327-1348, 1969.Crossref 12. Carvalho AD, Giampaglia CM, Kimura H, et al: Maternal and infant antibody response to meningococcal vaccination in pregnancy . Lancet 2:809-811, 1977.Crossref 13. Faur YC, Weisburd MH, Wilson MD: Isolation of Neisseria meningitidis from the genitourinary tract and anal canal . J Clin Microbiol 2:178-182, 1975. 14. Judson FN, Ehret JM, Eickhoff TC: Anogenital infection with Neisseria meningitidis in homosexual men . J Infect Dis 137:458-463, 1978.Crossref 15. Manginello FP, Pascale JA, Wolfsdorf J: Neonatal meningococcemia . AJDC 133:651-652, 1979.
Journal
American Journal of Diseases of Children
– American Medical Association
Published: Apr 1, 1980
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References
Infectious Diseases of the Fetus and Newborn Infant
Klein JO, Marcy SM
Purulent meningitis of newborn infants: Elevenyear experience in the antibiotic era
Groover RV, Sutherland JM, Landing BH
Factors in the prognosis of meningococcal infection: Review of 63 cases with emphasis on recognition and management of the severely ill patient
Stiehm ER, Damrosch DS
The Critically Ill Child
Hodes HL
Exchange transfusion with citrated whole blood for disseminated intravascular coagulation
Gross S, Melhorn DK
Hypokalemia as a consistent feature of fulminant meningococcal septicaemia
Mauger DC
Neonatal meningococcal meningitis: Report of a case acquired in the nursery
Stiehm ER, Damrosch DS
Meningococcemia in a newborn infant whose mother had meningococcal vaginitis
Sunderland WA, Harris HH, Spence DA, et al
Fatal neonatal meningococcal meningitis: Association with maternal cervical-vaginal colonization
Jones RN, Slepack J, Eades A
Human immunity to the meningococcus: I. The role of humoral antibodies
Goldschneider I, Gotschlich EC, Artenstein MS
Human immunity to the meningococcus: II. Development of natural immunity
Goldschneider I, Gotschlich EC, Artenstein MS
Maternal and infant antibody response to meningococcal vaccination in pregnancy
Carvalho AD, Giampaglia CM, Kimura H, et al
Isolation of Neisseria meningitidis from the genitourinary tract and anal canal
Faur YC, Weisburd MH, Wilson MD
Anogenital infection with Neisseria meningitidis in homosexual men
Judson FN, Ehret JM, Eickhoff TC
Neonatal meningococcemia
Manginello FP, Pascale JA, Wolfsdorf J
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