Abstract • Neisseria meningitidis is a rare cause of infection in infants younger than 2 months of age, presumably because of transplacental passage of protective maternal antibodies. In most reported cases of meningococcal disease in neonates, a relatively mild clinical course has been observed. A 25-day-old infant survived acute, severe meningococcemia due to group B N meningitidis. This organism should be considered when neonates have signs of septicemia, especially in the presence of cutaneous petechiae and purpura. (Am J Dis Child 134:354-355, 1980) References 1. Klein JO, Marcy SM: Bacterial infections , in Remington JS, Klein JO (eds): Infectious Diseases of the Fetus and Newborn Infant . Philadelphia, WB Saunders Co, 1976, p 747. 2. Groover RV, Sutherland JM, Landing BH: Purulent meningitis of newborn infants: Elevenyear experience in the antibiotic era . N Engl J Med 264:1115-1121, 1961.Crossref 3. Stiehm ER, Damrosch DS: Factors in the prognosis of meningococcal infection: Review of 63 cases with emphasis on recognition and management of the severely ill patient . J Pediatr 68:457-467, 1966.Crossref 4. Hodes HL: Endotoxin shock , in Smith CA (ed): The Critically Ill Child , ed 2. Philadelphia, WB Saunders Co, 1977, pp 25-45. 5. Gross S, Melhorn DK: Exchange transfusion with citrated whole blood for disseminated intravascular coagulation . J Pediatr 78:415-419, 1971.Crossref 6. Mauger DC: Hypokalemia as a consistent feature of fulminant meningococcal septicaemia . Aust Paediatr J 7:84-86, 1971. 7. Stiehm ER, Damrosch DS: Neonatal meningococcal meningitis: Report of a case acquired in the nursery . J Pediatr 68:654-656, 1966.Crossref 8. Sunderland WA, Harris HH, Spence DA, et al: Meningococcemia in a newborn infant whose mother had meningococcal vaginitis . J Pediatr 81:856, 1972.Crossref 9. Jones RN, Slepack J, Eades A: Fatal neonatal meningococcal meningitis: Association with maternal cervical-vaginal colonization . JAMA 236:2652-2653, 1976.Crossref 10. Goldschneider I, Gotschlich EC, Artenstein MS: Human immunity to the meningococcus: I. The role of humoral antibodies . J Exp Med 129:1307-1326, 1969.Crossref 11. Goldschneider I, Gotschlich EC, Artenstein MS: Human immunity to the meningococcus: II. Development of natural immunity . J Exp Med 129:1327-1348, 1969.Crossref 12. Carvalho AD, Giampaglia CM, Kimura H, et al: Maternal and infant antibody response to meningococcal vaccination in pregnancy . Lancet 2:809-811, 1977.Crossref 13. Faur YC, Weisburd MH, Wilson MD: Isolation of Neisseria meningitidis from the genitourinary tract and anal canal . J Clin Microbiol 2:178-182, 1975. 14. Judson FN, Ehret JM, Eickhoff TC: Anogenital infection with Neisseria meningitidis in homosexual men . J Infect Dis 137:458-463, 1978.Crossref 15. Manginello FP, Pascale JA, Wolfsdorf J: Neonatal meningococcemia . AJDC 133:651-652, 1979.
American Journal of Diseases of Children – American Medical Association
Published: Apr 1, 1980
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