Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Fulminant Hyperthermia During Anesthesia and Surgery

Fulminant Hyperthermia During Anesthesia and Surgery Rapid, progressive hyperpyrexia is becoming a cause for concern. It occurred in 12 patients, ten of whom failed to survive the acute episode. Conventional anesthetic drugs, including thiopental sodium, succinylcholine chloride, nitrous oxide, and halothane, were employed in most of the patients. No specific signs or symptoms heralded the onset of the hyperthermia. Usually the first observation was that the skin of the patient felt very hot; cardiovascular collapse developed shortly thereafter. At the moment, the primary treatment is prophylactic: continual monitoring of body temperature will detect beginning increases in body heat and permit efforts to reverse the situation before it becomes irreversible. When the syndrome develops, drastic measures must be instituted at once to reduce body temperature, provide high concentrations of oxygen with hyperventilation, and combat metabolic acidosis. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Fulminant Hyperthermia During Anesthesia and Surgery

Stephen, Charles R.
JAMA , Volume 202 (3) – Oct 16, 1967
Download PDF
5 pages

Loading next page...
 
/lp/american-medical-association/fulminant-hyperthermia-during-anesthesia-and-surgery-8GkhLxi7T0

References (18)

Publisher
American Medical Association
Copyright
Copyright © 1967 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1967.03130160052008
Publisher site
See Article on Publisher Site

Abstract

Rapid, progressive hyperpyrexia is becoming a cause for concern. It occurred in 12 patients, ten of whom failed to survive the acute episode. Conventional anesthetic drugs, including thiopental sodium, succinylcholine chloride, nitrous oxide, and halothane, were employed in most of the patients. No specific signs or symptoms heralded the onset of the hyperthermia. Usually the first observation was that the skin of the patient felt very hot; cardiovascular collapse developed shortly thereafter. At the moment, the primary treatment is prophylactic: continual monitoring of body temperature will detect beginning increases in body heat and permit efforts to reverse the situation before it becomes irreversible. When the syndrome develops, drastic measures must be instituted at once to reduce body temperature, provide high concentrations of oxygen with hyperventilation, and combat metabolic acidosis.

Journal

JAMA – American Medical Association

Published: Oct 16, 1967

There are no references for this article.