Abstract In a patient with fronto-metaphyseal dysplasia, progressive joint deformities and osteolytic changes in the carpal bones observed suggest that this condition is a "heritable disorder of connective tissue." Metachromatic granules were demonstrated in cultured fibroblastic cells. References 1. Gorlin RJ, Cohen MM: Frontometaphyseal dysplasia: A new syndrome . Amer J Dis Child 118:487-494, 1969.Crossref 2. Holt JF: Yearbook of Pediatric Radiology . Chicago, Year Book Medical Publishers Inc, 1971, p 238. 3. McKusick VA: Heritable Disorders of Connective Tissue , ed 3. St. Louis, CV Mosby Co, 1966.
American Journal of Diseases of Children – American Medical Association
Published: Mar 1, 1972