Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

Folic Acid Supplements in Pregnancy and Severe Language Delay in Children

Folic Acid Supplements in Pregnancy and Severe Language Delay in Children ORIGINAL CONTRIBUTION Folic Acid Supplements in Pregnancy and Severe Language Delay in Children Christine Roth, MSc, ClinPsyD Context Prenatal folic acid supplements reduce the risk of neural tube defects and may have beneficial effects on other aspects of neurodevelopment. Per Magnus, MD, PhD Synnve Schjølberg, MSc, ClinPsyD Objective To examine associations between mothers’ use of prenatal folic acid supple- ments and risk of severe language delay in their children at age 3 years. Camilla Stoltenberg, MD, PhD Design, Setting, and Patients The prospective observational Norwegian Mother and Pa ˚ l Sure ´ n, MD, MPH Child Cohort Study recruited pregnant women between 1999 and December 2008. Data Ian W. McKeague, PhD on children born before 2008 whose mothers returned the 3-year follow-up questionnaire by June 16, 2010, were used. Maternal use of folic acid supplements within the interval George Davey Smith, MD, DSc from 4 weeks before to 8 weeks after conception was the exposure. Relative risks were Ted Reichborn-Kjennerud, MD, PhD approximated by estimating odds ratios (ORs) with 95% CIs in a logistic regression analysis. Ezra Susser, MD, DrPH Main Outcome Measure Children’s language competency at age 3 years mea- sured by maternal report on a 6-point ordinal http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Loading next page...
 
/lp/american-medical-association/folic-acid-supplements-in-pregnancy-and-severe-language-delay-in-whpSG24ZjE
Publisher
American Medical Association
Copyright
Copyright 2011 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2011.1433
pmid
21990300
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL CONTRIBUTION Folic Acid Supplements in Pregnancy and Severe Language Delay in Children Christine Roth, MSc, ClinPsyD Context Prenatal folic acid supplements reduce the risk of neural tube defects and may have beneficial effects on other aspects of neurodevelopment. Per Magnus, MD, PhD Synnve Schjølberg, MSc, ClinPsyD Objective To examine associations between mothers’ use of prenatal folic acid supple- ments and risk of severe language delay in their children at age 3 years. Camilla Stoltenberg, MD, PhD Design, Setting, and Patients The prospective observational Norwegian Mother and Pa ˚ l Sure ´ n, MD, MPH Child Cohort Study recruited pregnant women between 1999 and December 2008. Data Ian W. McKeague, PhD on children born before 2008 whose mothers returned the 3-year follow-up questionnaire by June 16, 2010, were used. Maternal use of folic acid supplements within the interval George Davey Smith, MD, DSc from 4 weeks before to 8 weeks after conception was the exposure. Relative risks were Ted Reichborn-Kjennerud, MD, PhD approximated by estimating odds ratios (ORs) with 95% CIs in a logistic regression analysis. Ezra Susser, MD, DrPH Main Outcome Measure Children’s language competency at age 3 years mea- sured by maternal report on a 6-point ordinal

Journal

JAMAAmerican Medical Association

Published: Oct 12, 2011

References