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Focal Motor Seizures

Focal Motor Seizures Abstract To the Editor.— In their recent article in the Archives (33:536, 1976), Collins et al report that the uptake of carbon 14-labeled 2-deoxyglucose is increased in the thalamus during severe focal seizures with or without bilateral spread; they attribute the changes in their autoradiographs to increased neuronal metabolism associated with seizure spread. A number of years ago, my associates and I1 reported a study of the influence of 25% CO2 on the uptake of sulfur 35-labeled sulfate by brain and demonstrated autoradiographic changes that are very similar in appearance to those of Collins and co-workers, that is, a patchy increase in radioactivity in the thalamus of some animals. We referred in that article to still earlier studies by Lee and Olszewski2 and Rozdilsky and Olszewski3 who demonstrated a similar pattern in animals subjected to electroshock in studies using radioiodine-labeled albumin. We concluded that the changes in both studies were References 1. Goldberg MA, Barlow CF, Roth LJ: Abnormal brain permeability in CO2 narcosis . Arch Neurol 9:66, 1963.Crossref 2. Lee JC, Olszewski J: Increased cerebrovascular permeability after repeated electroshocks . Neurology 11:515, 1961.Crossref 3. Rozdilsky B, Olszewski J: Permeability of cerebral blood vessels studied by radioactive iodinated bovine albumin . Neurolgy 7:270, 1957.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Neurology American Medical Association

Focal Motor Seizures

Archives of Neurology , Volume 34 (1) – Jan 1, 1977

Focal Motor Seizures

Abstract

Abstract To the Editor.— In their recent article in the Archives (33:536, 1976), Collins et al report that the uptake of carbon 14-labeled 2-deoxyglucose is increased in the thalamus during severe focal seizures with or without bilateral spread; they attribute the changes in their autoradiographs to increased neuronal metabolism associated with seizure spread. A number of years ago, my associates and I1 reported a study of the influence of 25% CO2 on the uptake of sulfur 35-labeled...
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Publisher
American Medical Association
Copyright
Copyright © 1977 American Medical Association. All Rights Reserved.
ISSN
0003-9942
eISSN
1538-3687
DOI
10.1001/archneur.1977.00500130077016
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor.— In their recent article in the Archives (33:536, 1976), Collins et al report that the uptake of carbon 14-labeled 2-deoxyglucose is increased in the thalamus during severe focal seizures with or without bilateral spread; they attribute the changes in their autoradiographs to increased neuronal metabolism associated with seizure spread. A number of years ago, my associates and I1 reported a study of the influence of 25% CO2 on the uptake of sulfur 35-labeled sulfate by brain and demonstrated autoradiographic changes that are very similar in appearance to those of Collins and co-workers, that is, a patchy increase in radioactivity in the thalamus of some animals. We referred in that article to still earlier studies by Lee and Olszewski2 and Rozdilsky and Olszewski3 who demonstrated a similar pattern in animals subjected to electroshock in studies using radioiodine-labeled albumin. We concluded that the changes in both studies were References 1. Goldberg MA, Barlow CF, Roth LJ: Abnormal brain permeability in CO2 narcosis . Arch Neurol 9:66, 1963.Crossref 2. Lee JC, Olszewski J: Increased cerebrovascular permeability after repeated electroshocks . Neurology 11:515, 1961.Crossref 3. Rozdilsky B, Olszewski J: Permeability of cerebral blood vessels studied by radioactive iodinated bovine albumin . Neurolgy 7:270, 1957.Crossref

Journal

Archives of NeurologyAmerican Medical Association

Published: Jan 1, 1977

References