Key PointsQuestionWhat is the long-term recurrence rate in patients with uncomplicated acute appendicitis treated with antibiotics? FindingsIn this 5-year observational follow-up of 257 patients initially treated with antibiotics for uncomplicated acute appendicitis, the cumulative incidence of recurrent appendicitis at 1, 2, 3, 4, and 5 years was 27.3% at 1 year, 34.0% at 2, 35.2% at 3, 37.1% at 4, and 39.1% at 5 years. MeaningLong-term follow up of patients with uncomplicated acute appendicitis suggests that initial treatment with antibiotics rather than surgery may be a feasible alternative.
JAMA – American Medical Association
Published: Sep 25, 2018