Abstract A case of fingerprint corneal dystrophy with epithelial cysts has been studied histologically, using ultrathin sections for light and electron microscopy. Fingerprint lines that are ensheathed in normal basement membrane consist of a fibrillogranular protein apparently a product of the corneal epithelium. They are continuous with a subepithelial seam of similar, friable material thus accounting for the ready dehiscence and recurrent breakdown of the epithelium. Moribund cells stimulate fusion of epithelial cells to form multinucleate giant cells. These seclude degenerating cells that thus sequestered are taken by centripetal cell movement toward the tear film where they are discharged. The histologic evidence suggests that fingerprint dystrophy, the microcystic dystrophy of Cogan, and the recurrent erosion syndrome are closely related disorders. References 1. Bron AJ, Brown NA: Some superficial corneal disorders . Trans Ophthalmol Soc UK 91:13-29, 1971. 2. Cogan DG, et al: Microcystic dystrophy of the corneal epithelium . Trans Am Ophthalmol Soc 62:213-225, 1964. 3. Guerry D: Observations on Cogan's microcystic dystrophy of the corneal epithelium . Trans Am Ophthalmol Soc 63:320-334, 1965. 4. Kaufman HE: Epithelial erosion syndrome: Metaherpetic keratitis . Am J Ophthalmol 57:983-987, 1964. 5. Tripathi RC, Bron AJ: Ultrastructural study of nontraumatic recurrent corneal erosion . Br J Ophthalmol 56:73-85, 1972.Crossref 6. Franceschetti A, et al: Clinical and social aspects of heredity in ophthalmology . Acta XVI Concilium Ophthalmologicum Britannia . London, British Medical Association, 1951, vol 1, pp 157-299. 7. Trobe JD, Laibson PR: Dystrophic changes in the anterior cornea . Arch Ophthalmol 87:378-382, 1972.Crossref 8. De Voe AG: Certain abnormalities of Bowman's membrane with particular reference to fingerprint lines in the cornea . Tr Am Ophthalmol Soc 60:195-201, 1962. 9. Chandler PA: Recurrent erosions of the cornea . Am J Ophthalmol 28:355-363, 1945. 10. Kaufman HE, Clower JW: Irregularities of Bowman's membrane . Am J Ophthalmol 61:227-230, 1966. 11. Guerry D: Fingerprint-like lines in the cornea . Am J Ophthalmol 33:724-727, 1950. 12. Graves B: A bilateral chronic affection of the endothelial face of the cornea of elderly persons with an account of the technical and clinical principles of its slitlamp observation . Br J Ophthalmol 8:502-544, 1924.Crossref 13. Zander E, Weddell G: Reaction of corneal nerve fibres . Br J Ophthalmol 35:61-88, 1951.Crossref 14. Dark AJ: Formed elements in the human lens capsule . Br J Ophthalmol 45:298-306, 1961.Crossref 15. Bertelson TI, Drablos PA, Flood PR: The so-called senile exfoliation (pseudoexfoliation) of the anterior lens capsule . Acta Ophthalmol 42:1096-1113, 1964.Crossref 16. Ashton N, et al: Electron microscopic study of pseudoexfoliation of the lens capsule . Invest Ophthalmol 4:141-161, 1965. 17. Dark AJ, Streeten BW, Jones D: Accumulation of fibrillar protein in the aging human lens capsule: With special reference to the pathogenesis of pseudoexfoliative disease of the lens . Arch Ophthalmol 82:815-821, 1969.Crossref 18. Henkind P, Prose P: Anterior polar cataract: Electron microscopic evidence of collagen . Am J Ophthalmol 63:768-771, 1967. 19. Goldsmith M: The anatomy of cell death . J Cell Biol 31:41, 1966. 20. Klion FM, Schaffner F: The ultrastructure of acidophilic councilman-like bodies in the liver . Am J Pathol 48:758-767, 1966. 21. Wilgram GF, et al: Sunburn effect on keratinosomes . Arch Dermatol 101:505-519, 1970.Crossref 22. Kerr JFR, Wyllie AH, Currie AR: Aproptosis: A basic biological phenomenon with wide ranging implications in tissue kinetics . Br J Cancer 26:239-255, 1972.Crossref 23. Kuwabara T, Ciccarelli EC: Meesmann's corneal dystrophy: A pathological study . Arch Ophthalmol 71:676-682, 1964.Crossref
Archives of Ophthalmology – American Medical Association
Published: Dec 1, 1974
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera