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FDA: Acetaminophen May Trigger Serious Skin Problems

FDA: Acetaminophen May Trigger Serious Skin Problems News & Analysis FDA: Acetaminophen May Trigger news@JAMA FROM JAMA’S DAILY NEWS SITE Serious Skin Problems Bridget M. Kuehn, MSJ he US Food and Drug Administra- reemergence of symptoms when later tion (FDA) has added acetamino- reexposed to acetaminophen. The review T phen to the list of pain relievers that also identified several cases of serious skin mayinrarecasestriggerlife-threateningskin reactions after exposure to only acet- reactions. aminophen or in which skin sensitivity The FDA issued a warning in August tests suggested the reaction was caused that pain and fever reducer acetamino- by acetaminophen. A search of FAERS Statin-Antibiotic Interaction phen may cause Stevens-Johnson syn- between 1969 and 2012 identified 91 Some statins interact with certain antibiotics, putting older adults who take both at increased drome (SJS), toxic epidermal necrolysis cases of SJS or TEN and 16 cases of AGEP risk for hospitalization and death. (TEN), or acute generalized exanthema- in individuals who had taken acetamino- An analysis of medical records from about tous pustulosis (AGEP), conditions that phen, including 67 cases in which the indi- 73 000 older adults showed that taking statins may be fatal, based on a review of the vidual was hospitalized, and 12 deaths. and clarithromycin http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

FDA: Acetaminophen May Trigger Serious Skin Problems

JAMA , Volume 310 (8) – Aug 28, 2013

FDA: Acetaminophen May Trigger Serious Skin Problems

Abstract

News & Analysis FDA: Acetaminophen May Trigger news@JAMA FROM JAMA’S DAILY NEWS SITE Serious Skin Problems Bridget M. Kuehn, MSJ he US Food and Drug Administra- reemergence of symptoms when later tion (FDA) has added acetamino- reexposed to acetaminophen. The review T phen to the list of pain relievers that also identified several cases of serious skin mayinrarecasestriggerlife-threateningskin reactions after exposure to only acet- reactions. aminophen or in which skin sensitivity...
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Publisher
American Medical Association
Copyright
Copyright 2013 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2013.276938
pmid
23982356
Publisher site
See Article on Publisher Site

Abstract

News & Analysis FDA: Acetaminophen May Trigger news@JAMA FROM JAMA’S DAILY NEWS SITE Serious Skin Problems Bridget M. Kuehn, MSJ he US Food and Drug Administra- reemergence of symptoms when later tion (FDA) has added acetamino- reexposed to acetaminophen. The review T phen to the list of pain relievers that also identified several cases of serious skin mayinrarecasestriggerlife-threateningskin reactions after exposure to only acet- reactions. aminophen or in which skin sensitivity The FDA issued a warning in August tests suggested the reaction was caused that pain and fever reducer acetamino- by acetaminophen. A search of FAERS Statin-Antibiotic Interaction phen may cause Stevens-Johnson syn- between 1969 and 2012 identified 91 Some statins interact with certain antibiotics, putting older adults who take both at increased drome (SJS), toxic epidermal necrolysis cases of SJS or TEN and 16 cases of AGEP risk for hospitalization and death. (TEN), or acute generalized exanthema- in individuals who had taken acetamino- An analysis of medical records from about tous pustulosis (AGEP), conditions that phen, including 67 cases in which the indi- 73 000 older adults showed that taking statins may be fatal, based on a review of the vidual was hospitalized, and 12 deaths. and clarithromycin

Journal

JAMAAmerican Medical Association

Published: Aug 28, 2013

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