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Familial Comedones: Evidence for Autosomal Dominant Inheritance

Familial Comedones: Evidence for Autosomal Dominant Inheritance Abstract • Thirteen members of a family had multiple comedones. Three other relatives were also ascertained to be affected. This peculiar dermatosis affected both sexes and was present in one individual as young as 10 years of age. The lesions were more numerous in male family members, increasing in number with age. The pedigree showed a definite pattern of autosomal dominant inheritance. (Arch Dermatol 114:1807-1809, 1978) References 1. Rodin HH, Blankenship JL, Berstein G: Diffuse familial comedones . Arch Dermatol 95:145-146, 1967. 2. Carneiro SJC, Dickson JE, Knox JM: Familial dyskeratotic comedones . Arch Dermatol 105:249-251, 1972.Crossref 3. McKusick VA: Mendelian Inheritance in Man . Baltimore, Johns Hopkins University Press, 1975, p 63. 4. Cantú JM, Macotela-Ruiz E: Concordance of marginal keratoderma of the palms and Favre-Racouchot disease in MZ twins . Acta Genet Med Gemellol 24:321-322, 1975. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Familial Comedones: Evidence for Autosomal Dominant Inheritance

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Publisher
American Medical Association
Copyright
Copyright © 1978 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1978.01640240049016
Publisher site
See Article on Publisher Site

Abstract

Abstract • Thirteen members of a family had multiple comedones. Three other relatives were also ascertained to be affected. This peculiar dermatosis affected both sexes and was present in one individual as young as 10 years of age. The lesions were more numerous in male family members, increasing in number with age. The pedigree showed a definite pattern of autosomal dominant inheritance. (Arch Dermatol 114:1807-1809, 1978) References 1. Rodin HH, Blankenship JL, Berstein G: Diffuse familial comedones . Arch Dermatol 95:145-146, 1967. 2. Carneiro SJC, Dickson JE, Knox JM: Familial dyskeratotic comedones . Arch Dermatol 105:249-251, 1972.Crossref 3. McKusick VA: Mendelian Inheritance in Man . Baltimore, Johns Hopkins University Press, 1975, p 63. 4. Cantú JM, Macotela-Ruiz E: Concordance of marginal keratoderma of the palms and Favre-Racouchot disease in MZ twins . Acta Genet Med Gemellol 24:321-322, 1975.

Journal

Archives of DermatologyAmerican Medical Association

Published: Dec 1, 1978

References