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FAILURE OF AMINOACETIC ACID TO INCREASE THE WORK CAPACITY OF HUMAN SUBJECTS

FAILURE OF AMINOACETIC ACID TO INCREASE THE WORK CAPACITY OF HUMAN SUBJECTS During the past decade aminoacetic acid has been used in the treatment of various myopathies and currently is the subject of debate relative to its value in the treatment of fatigue and in increasing endurance. Aminoacetic acid is also known as glycine and glycocoll. It is present in most of the common proteins, and by chemical analyses1 one fourth of the protein, gelatin, has been shown to be aminoacetic acid. From 1927 to 1929 Brand, Harris, Sandberg and Ringer2 in their search for the precursor of creatine first gave aminoacetic acid to patients with progressive muscular dystrophy. Thomas, Milhorat and Techner3 in 1932 reported clinical improvement in certain patients with this disease after prolonged treatment with this amino acid. Brand and his co-workers4 in their original work, and later in 1933, and Boothby5 in 1934 failed to find such beneficial effect in patients with progressive http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

FAILURE OF AMINOACETIC ACID TO INCREASE THE WORK CAPACITY OF HUMAN SUBJECTS

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References (16)

Publisher
American Medical Association
Copyright
Copyright © 1942 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1942.02830080026006
Publisher site
See Article on Publisher Site

Abstract

During the past decade aminoacetic acid has been used in the treatment of various myopathies and currently is the subject of debate relative to its value in the treatment of fatigue and in increasing endurance. Aminoacetic acid is also known as glycine and glycocoll. It is present in most of the common proteins, and by chemical analyses1 one fourth of the protein, gelatin, has been shown to be aminoacetic acid. From 1927 to 1929 Brand, Harris, Sandberg and Ringer2 in their search for the precursor of creatine first gave aminoacetic acid to patients with progressive muscular dystrophy. Thomas, Milhorat and Techner3 in 1932 reported clinical improvement in certain patients with this disease after prolonged treatment with this amino acid. Brand and his co-workers4 in their original work, and later in 1933, and Boothby5 in 1934 failed to find such beneficial effect in patients with progressive

Journal

JAMAAmerican Medical Association

Published: Feb 21, 1942

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