Abstract This report presents one further detail in the investigation of factors which are responsible for the resistance to outflow of aqueous humor from the eye. One portion of this study which has already been reported was concerned with tonographic determination of facility and rate of outflow of aqueous humor in patients *; another portion has been experimental, concerned with measurement of facility of outflow from enucleated eyes, both normal and glaucomatous.† It has been shown that the facility of outflow from enucleated eyes differs by only about 10% from that found in vivo by tonography.4 Furthermore, the external two-thirds of the perilimbal sclera, with its included portions of the outflow channels, can be removed from enucleated normal human eyes without appreciably increasing the facility of outflow.5 It has appeared from these findings that the principal anatomic resistance to flow is to be found in the immediate neighborhood of Schlemm's References 1. References 1, 2, and 3. 2. References 4 and 5. 3. Grant, W. M.: Tonographic Method for Measuring the Facility and Rate of Aqueous Flow in Human Eyes , Arch. Ophth. 44:204-214, 1950.Crossref 4. Grant, W. M.: Clinical Measurements of Aqueous Outflow , A. M. A. Arch. Ophth. 46:113-131, 1951.Crossref 5. Grant, W. M., and Trotter, R. R.: Outflow of the Intraocular Fluid: Clinical Aspect, Council for International Organizations of Medical Sciences Symposium on Glaucoma, 1954, Oxford, Blackwell Scientific Publications, Ltd., to be published. 6. Grant, W. M., and Trotter, R. R.: Tonographic Measurements in Enucleated Eyes , A. M. A. Arch. Ophth. 53:191-200, 1955.Crossref 7. Grant, W. M., and Trotter, R. R.: Factors Responsible for the Resistance to Outflow of the Intraocular Fluid, Proc. 17th International Congress of Ophthalmology, to be published. 8. Perkins, E. S.: Pressure in the Canal of Schlemm , Brit. J. Ophth. 39:215-219, 1955.Crossref 9. Linner, E.: The Episcleral Venous Pressure During Tonography, Proc. 17th International Congress of Ophthalmology, to be published.
A.M.A. Archives of Ophthalmology – American Medical Association
Published: Aug 1, 1955
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