Key PointsQuestionHow accurately does the Epic Sepsis Model, a proprietary sepsis prediction model implemented at hundreds of US hospitals, predict the onset of sepsis? FindingsIn this cohort study of 27 697 patients undergoing 38 455 hospitalizations, sepsis occurred in 7% of the hosptalizations. The Epic Sepsis Model predicted the onset of sepsis with an area under the curve of 0.63, which is substantially worse than the performance reported by its developer. MeaningThis study suggests that the Epic Sepsis Model poorly predicts sepsis; its widespread adoption despite poor performance raises fundamental concerns about sepsis management on a national level.
JAMA Internal Medicine – American Medical Association
Published: Aug 21, 2021