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EXSUFFLATION WITH NEGATIVE PRESSURE (E.W.N.P.): Elimination of Radiopaque Material and Foreign Bodies from Bronchi of Anesthetized Dogs

EXSUFFLATION WITH NEGATIVE PRESSURE (E.W.N.P.): Elimination of Radiopaque Material and Foreign... Abstract THE ELIMINATION of radiopaque material from the tracheobronchial tree of anesthetized dogs was reported in a previous paper.1 This was accomplished by two devices which produced high-volume expiratory-flow rates simulating the natural cough.* Studies of bronchial dynamics by serial bronchography revealed a twofold dilatation of the medium-sized bronchi in animals subjected to an inflationary pressure of + 40 mm. Hg. The restoration to normal of the blood gas values found in obstructive dyspnea, reported by Cherniack, Gordon, and Drimmer,5 may be explained in part by the marked dilatation of the bronchi. The development of a more effective technique, whereby there is slow inflation of the lungs, followed by an "explosive expiration," resulted in a total pressure-drop of approximately 100 mm. Hg, with expiratory-flow rates that surpassed those attainable by the most vigorous cough of normal human subjects.6 A positive pressure blower served to inflate the lungs to a References 1. References 2-4. 2. Bickerman, H. A.; Beck, G. J.; Gordon, C., and Barach, A. L.: Physical Methods Simulating Mechanisms of the Human Cough: Elimination of Radiopaque Material from the Bronchi of Dogs , J. Appl. Physiol. 5:92, 1952. 3. Barach, A. L.; Beck, G. J.; Bickerman, H. A., and Seanor, H. E.: Mechanical Coughing: Studies on Physical Methods of Producing High Velocity Flow Rates During the Expiratory Cycle , Tr. A. Am. Physicians 64:360, 1951. 4. Barach, A. L.; Beck, G. J.; Bickerman, H. A., and Seanor, H. E.: Physical Methods Simulating Cough Mechanisms: Use in Poliomyelitis, Bronchial Asthma, Pulmonary Emphysema, and Bronchiectasis , J. A. M. A. 150:1380, 1952.Crossref 5. Barach, A. L.; Beck, G. J.; Bickerman, H. A., and Seanor, H. E.: Physical Methods Simulating Mechanisms of the Human Cough , J. Appl. Physiol. 5:85, 1952. 6. Cherniack, R.; Gordon, C., and Drimmer, F.: Physiological Effects of Mechanical Exsufflation on Experimental Obstructive Breathing in Human Subjects , J. Clin. Invest. 12:1028, 1952.Crossref 7. Barach, A. L.; Beck, G. J., and Smith, W.: Mechanical Production of Expiratory Flow Rates Surpassing the Capacity of Human Coughing , Am. J. M. Sc. 226:241, 1953.Crossref 8. Barach, A. L., and Beck, G. J.: Exsufflation with Negative Pressure: Physiological and Clinical Studies in Poliomyelitis, Bronchial Asthma, Pulmonary Emphysema, and Bronchiectasis , A. M. A. Arch. Int. Med. , to be published. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Internal Medicine American Medical Association

EXSUFFLATION WITH NEGATIVE PRESSURE (E.W.N.P.): Elimination of Radiopaque Material and Foreign Bodies from Bronchi of Anesthetized Dogs

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Publisher
American Medical Association
Copyright
Copyright © 1954 American Medical Association. All Rights Reserved.
ISSN
0888-2479
DOI
10.1001/archinte.1954.00240290056006
Publisher site
See Article on Publisher Site

Abstract

Abstract THE ELIMINATION of radiopaque material from the tracheobronchial tree of anesthetized dogs was reported in a previous paper.1 This was accomplished by two devices which produced high-volume expiratory-flow rates simulating the natural cough.* Studies of bronchial dynamics by serial bronchography revealed a twofold dilatation of the medium-sized bronchi in animals subjected to an inflationary pressure of + 40 mm. Hg. The restoration to normal of the blood gas values found in obstructive dyspnea, reported by Cherniack, Gordon, and Drimmer,5 may be explained in part by the marked dilatation of the bronchi. The development of a more effective technique, whereby there is slow inflation of the lungs, followed by an "explosive expiration," resulted in a total pressure-drop of approximately 100 mm. Hg, with expiratory-flow rates that surpassed those attainable by the most vigorous cough of normal human subjects.6 A positive pressure blower served to inflate the lungs to a References 1. References 2-4. 2. Bickerman, H. A.; Beck, G. J.; Gordon, C., and Barach, A. L.: Physical Methods Simulating Mechanisms of the Human Cough: Elimination of Radiopaque Material from the Bronchi of Dogs , J. Appl. Physiol. 5:92, 1952. 3. Barach, A. L.; Beck, G. J.; Bickerman, H. A., and Seanor, H. E.: Mechanical Coughing: Studies on Physical Methods of Producing High Velocity Flow Rates During the Expiratory Cycle , Tr. A. Am. Physicians 64:360, 1951. 4. Barach, A. L.; Beck, G. J.; Bickerman, H. A., and Seanor, H. E.: Physical Methods Simulating Cough Mechanisms: Use in Poliomyelitis, Bronchial Asthma, Pulmonary Emphysema, and Bronchiectasis , J. A. M. A. 150:1380, 1952.Crossref 5. Barach, A. L.; Beck, G. J.; Bickerman, H. A., and Seanor, H. E.: Physical Methods Simulating Mechanisms of the Human Cough , J. Appl. Physiol. 5:85, 1952. 6. Cherniack, R.; Gordon, C., and Drimmer, F.: Physiological Effects of Mechanical Exsufflation on Experimental Obstructive Breathing in Human Subjects , J. Clin. Invest. 12:1028, 1952.Crossref 7. Barach, A. L.; Beck, G. J., and Smith, W.: Mechanical Production of Expiratory Flow Rates Surpassing the Capacity of Human Coughing , Am. J. M. Sc. 226:241, 1953.Crossref 8. Barach, A. L., and Beck, G. J.: Exsufflation with Negative Pressure: Physiological and Clinical Studies in Poliomyelitis, Bronchial Asthma, Pulmonary Emphysema, and Bronchiectasis , A. M. A. Arch. Int. Med. , to be published.

Journal

A.M.A. Archives of Internal MedicineAmerican Medical Association

Published: May 1, 1954

References