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EXPERIMENTAL SHOCK: IX. A STUDY OF THE EFFECTS OF THE LOSS OF WHOLE BLOOD, OF BLOOD PLASMA AND OF RED BLOOD CELLS

EXPERIMENTAL SHOCK: IX. A STUDY OF THE EFFECTS OF THE LOSS OF WHOLE BLOOD, OF BLOOD PLASMA AND OF... Abstract In previous experiments,1 the amount of fluid that was lost from the blood vessels in traumatized areas has been determined. The fluid that escapes from the blood vessels into an extremity as a result of severe trauma consists largely of whole blood. The composition of the fluid that escapes from or into the injured area as a result of mild trauma to an extremity, trauma to the intestines and burns of the body surface was found by Beard and one of us (A. B.)2 to be nearly identical with that of the blood plasma. These experiments were all performed on dogs anesthetized by barbital. It was believed that the loss of fluid from the blood vessels in the injured area was the chief if not the sole factor in the production of the low blood pressure. The present experiments were undertaken in order to determine the tolerance of References 1. Blalock, Alfred: Experimental Shock: The Cause of the Low Blood Pressure Produced by Muscle Injury , Arch. Surg. 20:759 ( (June) ) 1930 2. Trauma to the Intestines: The Importance of the Local Loss of Fluid in the Production of the Low Blood Pressure , Blalock Arch. Surg. 22:314 ( (Feb.) ) 1931Crossref 3. Experimental Shock: VI. The Probable Cause for the Reduction in the Blood Pressure Following Mild Trauma to an Extremity, this issue, p. 598 4. Experimental Shock: VII. The Importance of the Local Loss of Fluid in the Production of the Low Blood Pressure After Burns, this issue, p. 610. 5. Beard, J. W., and Blalock, A.: Experimental Shock: VIII. The Compasition of the Fluid That Escapes from the Blood Stream After Mild Trauma to an Extremity, After Trauma to the Intestines, and After Burns, Arch. Surg., this issue, p. 617. 6. Blalock (footnote 1, first reference). 7. Blalock (footnote 1, second reference). 8. Harris, P. N., and Blalock, A.: Unpublished Observations on the Water Content of the Tissues After Hemorrhage and After Trauma. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

EXPERIMENTAL SHOCK: IX. A STUDY OF THE EFFECTS OF THE LOSS OF WHOLE BLOOD, OF BLOOD PLASMA AND OF RED BLOOD CELLS

Archives of Surgery , Volume 22 (4) – Apr 1, 1931

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Publisher
American Medical Association
Copyright
Copyright © 1931 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1931.01160040102007
Publisher site
See Article on Publisher Site

Abstract

Abstract In previous experiments,1 the amount of fluid that was lost from the blood vessels in traumatized areas has been determined. The fluid that escapes from the blood vessels into an extremity as a result of severe trauma consists largely of whole blood. The composition of the fluid that escapes from or into the injured area as a result of mild trauma to an extremity, trauma to the intestines and burns of the body surface was found by Beard and one of us (A. B.)2 to be nearly identical with that of the blood plasma. These experiments were all performed on dogs anesthetized by barbital. It was believed that the loss of fluid from the blood vessels in the injured area was the chief if not the sole factor in the production of the low blood pressure. The present experiments were undertaken in order to determine the tolerance of References 1. Blalock, Alfred: Experimental Shock: The Cause of the Low Blood Pressure Produced by Muscle Injury , Arch. Surg. 20:759 ( (June) ) 1930 2. Trauma to the Intestines: The Importance of the Local Loss of Fluid in the Production of the Low Blood Pressure , Blalock Arch. Surg. 22:314 ( (Feb.) ) 1931Crossref 3. Experimental Shock: VI. The Probable Cause for the Reduction in the Blood Pressure Following Mild Trauma to an Extremity, this issue, p. 598 4. Experimental Shock: VII. The Importance of the Local Loss of Fluid in the Production of the Low Blood Pressure After Burns, this issue, p. 610. 5. Beard, J. W., and Blalock, A.: Experimental Shock: VIII. The Compasition of the Fluid That Escapes from the Blood Stream After Mild Trauma to an Extremity, After Trauma to the Intestines, and After Burns, Arch. Surg., this issue, p. 617. 6. Blalock (footnote 1, first reference). 7. Blalock (footnote 1, second reference). 8. Harris, P. N., and Blalock, A.: Unpublished Observations on the Water Content of the Tissues After Hemorrhage and After Trauma.

Journal

Archives of SurgeryAmerican Medical Association

Published: Apr 1, 1931

References