Abstract Injection of radioactive fat emboli into the internal carotid artery of rabbits resulted in rapid death in some animals. Death was preceded by hypertension and Cheyne-Stokes respirations. These animals showed an increased retention of fat emboli within the brain, and a disproportionately high recovery from the pons and midbrain, compared to animals which were killed. The data suggest that the death mechanism was brain stem ischemia followed by a vasomotor ischemic reflex, which in turn resulted in vasospasm and hypertension. The choroid plexus was found to be the most efficient filter for fat emboli within the brain on a per gram basis. References 1. Soloway HB, Aronson SM: Atheromatous embolism to the central nervous system: Report of 16 cases . Arch Neurol 11:657-667, 1964.Crossref 2. Soloway HB, Robinson EF, Hufnagel HV, et al: Experimental fat embolism . Arch Path 88:171-174, 1969. 3. Donaghy RMP, Collier JF: Study in experimental fat embolism . Trans New Eng Surg Soc 43:82, 1962. 4. Cobb CA Jr, Lequire VS, Gray ME, et al: Therapy of traumatic fat embolism with intravenous fluids and heparin . Surg Forum 9:751, 1958. 5. Soloway HB, Rhines R, Ford HH: Effect of aminophylline on the blood volume of the brain of the white rat . Acta Neurol Scand 39:179-186, 1963.Crossref 6. Porter WT: Shock from fat embolism of the vasomotor centre . Amer J Physiol 71:277-315, 1924. 7. Soloway HB, Robinson EF, Sleeman HK, et al: Resolution of experimental fat embolism . Arch Path 90:230-234, 1970.
Archives of Neurology – American Medical Association
Published: May 1, 1971
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera