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EXCRETION OF CREATINE AND CREATININE

EXCRETION OF CREATINE AND CREATININE During studies on creatine and creatinine metabolism, the hourly excretion of these substances was determined in two cases of muscular dystrophy, one case of chronic anterior poliomyelitis and in two normal boys. Shaffer1 found that the excretion of creatinine was constant throughout a twenty-four hour period as well as from day to day. Since that time cases have been studied which show that this constancy is not always found. Fluctuation in creatinine output during short fasts was noted by Neuwirth.2 Schultz3 found periodic variations in creatinine excretion during the day, irrespective of diet or sleep. Definite increases occurred at from 9 to 11a. m., 3 to 5 p. m. and 9 to 11 p. m. He found the creatinine output at night to be slightly less than that during the day. Simpson4 considered the urine volume to be a factor in variations in the creatinine excretion http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

EXCRETION OF CREATINE AND CREATININE

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References (4)

Publisher
American Medical Association
Copyright
Copyright © 1932 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1932.01950020054006
Publisher site
See Article on Publisher Site

Abstract

During studies on creatine and creatinine metabolism, the hourly excretion of these substances was determined in two cases of muscular dystrophy, one case of chronic anterior poliomyelitis and in two normal boys. Shaffer1 found that the excretion of creatinine was constant throughout a twenty-four hour period as well as from day to day. Since that time cases have been studied which show that this constancy is not always found. Fluctuation in creatinine output during short fasts was noted by Neuwirth.2 Schultz3 found periodic variations in creatinine excretion during the day, irrespective of diet or sleep. Definite increases occurred at from 9 to 11a. m., 3 to 5 p. m. and 9 to 11 p. m. He found the creatinine output at night to be slightly less than that during the day. Simpson4 considered the urine volume to be a factor in variations in the creatinine excretion

Journal

American journal of diseases of children – American Medical Association

Published: Feb 1, 1932

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