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Evaluation of Topical Corticosteroid Use in Pregnancy and Risk of Newborns Being Small for Gestational Age and Having Low Birth Weight

Evaluation of Topical Corticosteroid Use in Pregnancy and Risk of Newborns Being Small for... Key PointsQuestionDoes topical corticosteroid use in pregnancy increase the risks of the newborn being small for gestational age or having low birth weight? FindingsThis cohort study of 1.1 million pregnancies included all 60 498 pregnancies (60 497 matched) exposed to topical corticosteroids in Denmark from 1997 through 2016. No association was found between topical corticosteroid use during pregnancy and increased risks of newborns being small for gestational age or having low birth weight, regardless of corticosteroid potency and amount used. MeaningThese findings suggest that a moderate to large increase in the risk of newborns being small for gestational age or having low birth weight with corticosteroid use in pregnancy is unlikely, even when large amounts of potent to very potent topical corticosteroids are used. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Dermatology American Medical Association

Evaluation of Topical Corticosteroid Use in Pregnancy and Risk of Newborns Being Small for Gestational Age and Having Low Birth Weight

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Publisher
American Medical Association
Copyright
Copyright 2021 American Medical Association. All Rights Reserved.
ISSN
2168-6068
eISSN
2168-6084
DOI
10.1001/jamadermatol.2021.1090
Publisher site
See Article on Publisher Site

Abstract

Key PointsQuestionDoes topical corticosteroid use in pregnancy increase the risks of the newborn being small for gestational age or having low birth weight? FindingsThis cohort study of 1.1 million pregnancies included all 60 498 pregnancies (60 497 matched) exposed to topical corticosteroids in Denmark from 1997 through 2016. No association was found between topical corticosteroid use during pregnancy and increased risks of newborns being small for gestational age or having low birth weight, regardless of corticosteroid potency and amount used. MeaningThese findings suggest that a moderate to large increase in the risk of newborns being small for gestational age or having low birth weight with corticosteroid use in pregnancy is unlikely, even when large amounts of potent to very potent topical corticosteroids are used.

Journal

JAMA DermatologyAmerican Medical Association

Published: Jul 5, 2021

References