Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

Evaluation of Polyhexamethylene Biguanide (PHMB) as a Disinfectant for Adenovirus

Evaluation of Polyhexamethylene Biguanide (PHMB) as a Disinfectant for Adenovirus LABORATORY SCIENCES Evaluation of Polyhexamethylene Biguanide (PHMB) as a Disinfectant for Adenovirus Eric G. Romanowski, MS; Kathleen A. Yates, BS; Katherine E. O’Connor, BS; Francis S. Mah, MD; Robert M. Q. Shanks, PhD; Regis P. Kowalski, MS, M(ASCP) Importance: Swimming pools can be a vector for trans- tions relative to controls were calculated. Virucidal mission of adenovirus ocular infections. Polyhexameth- (99.9%) decreases in mean adenovirus titers after PHMB ylene biguanide (PHMB) is a disinfectant used in swim- treatment were determined for each adenovirus type and ming pools and hot tubs. temperature tested. Objective: To determine whether PHMB is an effec- Results: At room temperature, 50 ppm of PHMB pro- tive disinfectant against ocular adenovirus serotypes at duced mean reductions in titers less than 1 log for all a concentration used to disinfect swimming pools and adenovirus types tested. At 40C, 50 ppm of PHMB pro- hot tubs. duced mean reductions in titers less than 1 log for 2 adenovirus types and greater than 1 but less than 3 log Design: In vitro laboratory study. for 7 of 9 adenovirus types. Interventions: The direct disinfecting activity of PHMB Conclusions and Relevance: At a concentration of was determined in triplicate assays http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Ophthalmology American Medical Association

Evaluation of Polyhexamethylene Biguanide (PHMB) as a Disinfectant for Adenovirus

Loading next page...
 
/lp/american-medical-association/evaluation-of-polyhexamethylene-biguanide-phmb-as-a-disinfectant-for-7l1QtZXIdV
Publisher
American Medical Association
Copyright
Copyright 2013 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6165
eISSN
2168-6173
DOI
10.1001/jamaophthalmol.2013.2498
pmid
23450376
Publisher site
See Article on Publisher Site

Abstract

LABORATORY SCIENCES Evaluation of Polyhexamethylene Biguanide (PHMB) as a Disinfectant for Adenovirus Eric G. Romanowski, MS; Kathleen A. Yates, BS; Katherine E. O’Connor, BS; Francis S. Mah, MD; Robert M. Q. Shanks, PhD; Regis P. Kowalski, MS, M(ASCP) Importance: Swimming pools can be a vector for trans- tions relative to controls were calculated. Virucidal mission of adenovirus ocular infections. Polyhexameth- (99.9%) decreases in mean adenovirus titers after PHMB ylene biguanide (PHMB) is a disinfectant used in swim- treatment were determined for each adenovirus type and ming pools and hot tubs. temperature tested. Objective: To determine whether PHMB is an effec- Results: At room temperature, 50 ppm of PHMB pro- tive disinfectant against ocular adenovirus serotypes at duced mean reductions in titers less than 1 log for all a concentration used to disinfect swimming pools and adenovirus types tested. At 40C, 50 ppm of PHMB pro- hot tubs. duced mean reductions in titers less than 1 log for 2 adenovirus types and greater than 1 but less than 3 log Design: In vitro laboratory study. for 7 of 9 adenovirus types. Interventions: The direct disinfecting activity of PHMB Conclusions and Relevance: At a concentration of was determined in triplicate assays

Journal

JAMA OphthalmologyAmerican Medical Association

Published: Apr 1, 2013

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$499/year

Save searches from
Google Scholar,
PubMed

Create folders to
organize your research

Export folders, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month