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Evaluating an Evidence-Based Bundle for Preventing Surgical Site Infection

Evaluating an Evidence-Based Bundle for Preventing Surgical Site Infection ORIGINAL ARTICLE ONLINE FIRST Evaluating an Evidence-Based Bundle for Preventing Surgical Site Infection A Randomized Trial Thomas Anthony, MD, MSc; Bryce W. Murray, MD; John T. Sum-Ping, MD; Fima Lenkovsky, MD; Vadim D. Vornik, MD; Betty J. Parker, RN; Jackie E. McFarlin, RN, CIC; Kathleen Hartless, RN, CIC; Sergio Huerta, MD Objective: To determine if an evidence-based practice Main Outcome Measure: Overall SSI rate at 30 days bundle would result in a significantly lower rate of sur- assessed by blinded infection control coordinators using gical site infections (SSIs) when compared with stan- standardized definitions. dard practice. Results: The overall rate of SSI was 45% in the ex- Design: Single-institution, randomized controlled trial tended arm of the study and 24% in the standard arm with blinded assessment of main outcome. The trial (P=.003). Most of the increased number of infections in opened in April 2007 and was closed in January 2010. the extended arm were superficial incisional SSIs (36% extended arm vs 19% standard arm; P=.004). Multivar- Setting: Veterans Administration teaching hospital. iate analysis suggested that allocation to the extended arm of the trial conferred a 2.49-fold risk (95% confidence Patients: Patients who required elective transabdomi- interval, 1.36-4.56; P=.003) independent http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Surgery American Medical Association

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Publisher
American Medical Association
Copyright
Copyright 2011 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6254
eISSN
2168-6262
DOI
10.1001/archsurg.2010.249
pmid
21079110
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL ARTICLE ONLINE FIRST Evaluating an Evidence-Based Bundle for Preventing Surgical Site Infection A Randomized Trial Thomas Anthony, MD, MSc; Bryce W. Murray, MD; John T. Sum-Ping, MD; Fima Lenkovsky, MD; Vadim D. Vornik, MD; Betty J. Parker, RN; Jackie E. McFarlin, RN, CIC; Kathleen Hartless, RN, CIC; Sergio Huerta, MD Objective: To determine if an evidence-based practice Main Outcome Measure: Overall SSI rate at 30 days bundle would result in a significantly lower rate of sur- assessed by blinded infection control coordinators using gical site infections (SSIs) when compared with stan- standardized definitions. dard practice. Results: The overall rate of SSI was 45% in the ex- Design: Single-institution, randomized controlled trial tended arm of the study and 24% in the standard arm with blinded assessment of main outcome. The trial (P=.003). Most of the increased number of infections in opened in April 2007 and was closed in January 2010. the extended arm were superficial incisional SSIs (36% extended arm vs 19% standard arm; P=.004). Multivar- Setting: Veterans Administration teaching hospital. iate analysis suggested that allocation to the extended arm of the trial conferred a 2.49-fold risk (95% confidence Patients: Patients who required elective transabdomi- interval, 1.36-4.56; P=.003) independent

Journal

JAMA SurgeryAmerican Medical Association

Published: Mar 1, 2011

References