Abstract The term "neurocirculatory asthenia," adopted in America during the World War, and synonymous with the less satisfactory British expression "effort syndrome," was applied in an attempt to classify a large number of persons having symptoms referable to the cardiovascular system not dependent on any known pathologic process of the heart or blood vessels but often associated with a functional nervous disturbance. These symptoms were chiefly palpitation, shortness of breath, precordial pain or discomfort and exhaustion. One or more associated symptoms were often present: faintness, syncope, headache, dizziness, insomnia, increased perspiration, difficulty in swallowing, tremor, flushing and pallor. The borderline between the normal and the abnormal is ill defined, but neurocirculatory asthenia may be said to be present when the symptoms appear during such customary physical activities and excitements of daily life as previously caused no symptoms or which in the average person produce no symptoms. Neurocirculatory asthenia is of great References 1. Rothschild, M. A.: Neurocirculatory Asthenia , Bull. New York Acad. Med. 6:223, 1930. 2. Corvisart, J. N.: Essai sur les maladies et les lésions organiques du coeur et des gros vaisseaux , ed. 1, Paris, Migneret, 1806. 3. Flint, A.: Functional Disorder of the Heart, A Practical Treatise on the Diagnosis, Pathology and Treatment of Diseases of the Heart , Philadelphia, Blanchard & Lea, 1859, p. 403. 4. Da Costa, J. M.: On Irritable Heart , Am. J. M. Sc. 61:2, 1871.Crossref 5. Lewis, T.: The Soldier's Heart and the Effort Syndrome , New York, Paul B. Hoeber, Inc., 1919. 6. Brooks, H.: Syncope in Neurocirculatory Asthenia , Tr. A. Am. Physicians 39:419, 1924 7. Neurocirculatory Asthenia , M. Clin. North America 2:477, 1918 8. Functional Disturbances of the Heart , Philadelphia, J. B. Lippincott Company, 1932. 9. White, P. D., and Jones, T. D.: Heart Disease and Disorders in New England , Am. Heart J. 3:302, 1928.Crossref 10. White, P. D.: Cardiac Neuroses , in Nelson Loose Leaf Medicine , New York, T. Nelson & Sons, 1920, vol. 4, p. 635 11. 1931 edition, vol. 4, p. 447 12. An Important Consideration in the Analysis and Management of Heart Trouble: 4 Cases , New England J. Med. 199:148, 1928.Crossref 13. Lincoln, E. M.: The Hearts of Normal Children , Am. J. Dis. Child. 35: 398 ( (March) ) 1928.Crossref 14. Oppenheimer, B. S., and Rothschild, M. A.: The Psychoneurotic Factor in the Irritable Heart of Soldiers , J. A. M. A. 70:1919 ( (June 22) ) 1918.Crossref 15. Boas, E. P.: Neurogenic Disorders of the Heart , Am. J. M. Sc. 176:789, 1928. 16. Grant, R. T.: Observations on the After Histories of Men Suffering from the Effort Syndrome , Heart 12:121, 1925. 17. Gunewardene, H. O.: The Etiology of Effort Syndrome , Lancet 1:885, 1920.Crossref 18. White, P. D., and Hahn, R. G.: The Symptom of Sighing in Cardiovascular Diagnosis: With Spirographic Observations , Am. J. M. Sc. 177:179, 1929.Crossref 19. Kellogg, F., and White, P. D.: The Clinical Significance of Precordial Tenderness—The Relationship of Such Tenderness to Pain , New England J. Med. 206:659, 1932.Crossref 20. Culpin, M.: The Psychological Aspects of the Effort Syndrome , Lancet 2:184 ( (July 24) ) 1920.Crossref 21. White, P. D.: Heart Disease , New York, The Macmillan Company, 1931. 22. Crile, G. W.: Recurrent Hyperthyroidism, Neurocirculatory Asthenia and Peptic Ulcer: Treatment by Operations on the Suprarenal Sympathetic System , J. A. M. A. 97:1616 ( (Nov. 28) ) 1931Crossref 23. Denervation of the Adrenal Glands for Neurocirculatory Asthenia , Surg., Gynec. & Obst. 54:294, 1932.
Archives of Internal Medicine – American Medical Association
Published: May 1, 1934