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Etiological Factors in Manic-Depressive Psychoses

Etiological Factors in Manic-Depressive Psychoses Abstract • Fifty consecutive patients with bipolar affective psychosis are reviewed, and the genetic and electroencephalographic findings set against extant hypotheses about inheritance of the disorder and the etiological homogeneity of the syndrome. Inheritance in this sample appears usually not to be X-linked. The syndrome seems etiologically heterogeneous in that some patients have an early onset and prominent genetic determinants, while in others without apparent hereditary predisposition, the illness start later and show electroencephalographic evidence of cerebral dysfunction. References 1. Winokur G, Clayton PJ, Reich T: Manic Depressive Illness . St Louis, CV Mosby Co Publishers, 1969. 2. Helzer JE, Winokur G: A family interview study of male manic depressives . Arch Gen Psychiatry 31:73-77, 1974.Crossref 3. Goetzl U, Green R, Whybrow P, et al: X linkage revisited . Arch Gen Psychiatry 31:665-672, 1974.Crossref 4. Leonhard K, Korff I, Shulz H: Die Temperamente in den Familien der monopolaren und bipolaren phasischen Psychosen . Psychiatr Neurol 143:416-434, 1962.Crossref 5. Hays P: Modes of onset of psychotic depression . Br Med J 2:779-784, 1964.Crossref 6. Dálen P: Family history, the electroencephalogram, and perinatal factors in manic conditions . Acta Psychiatr Scand 41:527-563, 1965.Crossref 7. Slater E: The inheritance of manic-depressive insanity . Proc R Soc Med 29:981-990, 1936. 8. Perris C: A study of bipolar (manic-depressive) and unipolar recurrent depressive psychoses . Acta Psychiatr Scand 42, (suppl 194) , 1966. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of General Psychiatry American Medical Association

Etiological Factors in Manic-Depressive Psychoses

Archives of General Psychiatry , Volume 33 (10) – Oct 1, 1976

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Publisher
American Medical Association
Copyright
Copyright © 1976 American Medical Association. All Rights Reserved.
ISSN
0003-990X
eISSN
1598-3636
DOI
10.1001/archpsyc.1976.01770100049004
Publisher site
See Article on Publisher Site

Abstract

Abstract • Fifty consecutive patients with bipolar affective psychosis are reviewed, and the genetic and electroencephalographic findings set against extant hypotheses about inheritance of the disorder and the etiological homogeneity of the syndrome. Inheritance in this sample appears usually not to be X-linked. The syndrome seems etiologically heterogeneous in that some patients have an early onset and prominent genetic determinants, while in others without apparent hereditary predisposition, the illness start later and show electroencephalographic evidence of cerebral dysfunction. References 1. Winokur G, Clayton PJ, Reich T: Manic Depressive Illness . St Louis, CV Mosby Co Publishers, 1969. 2. Helzer JE, Winokur G: A family interview study of male manic depressives . Arch Gen Psychiatry 31:73-77, 1974.Crossref 3. Goetzl U, Green R, Whybrow P, et al: X linkage revisited . Arch Gen Psychiatry 31:665-672, 1974.Crossref 4. Leonhard K, Korff I, Shulz H: Die Temperamente in den Familien der monopolaren und bipolaren phasischen Psychosen . Psychiatr Neurol 143:416-434, 1962.Crossref 5. Hays P: Modes of onset of psychotic depression . Br Med J 2:779-784, 1964.Crossref 6. Dálen P: Family history, the electroencephalogram, and perinatal factors in manic conditions . Acta Psychiatr Scand 41:527-563, 1965.Crossref 7. Slater E: The inheritance of manic-depressive insanity . Proc R Soc Med 29:981-990, 1936. 8. Perris C: A study of bipolar (manic-depressive) and unipolar recurrent depressive psychoses . Acta Psychiatr Scand 42, (suppl 194) , 1966.

Journal

Archives of General PsychiatryAmerican Medical Association

Published: Oct 1, 1976

References