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Estrogen and Memory

Estrogen and Memory Researchers at the National Institute on Aging have another reason for postmenopausal women to consider estrogen replacement therapy: it may help slow normal, age-related declines in memory. In the December issue of Neurology, the researchers reported on 288 women enrolled in the Baltimore Longitudinal Study of Aging between 1978 and 1994. They compared scores on a visual memory test taken by 116 women receiving estrogen therapy with the scores of 172 women who had never used any type of hormone replacement. On average, the women taking estrogen scored about 2 fewer errors than women who were never treated with estrogen, which the researchers said was a significant difference. They also noted that the study was the first to document the effect of estrogen on visual memory; previous studies have indicated that estrogen may have an effect on verbal memory. Susan Resnick, PhD, principal investigator of the study, said animal studies have shown that estrogen can directly affect structural characteristics of neurons in regions of the brain that are vulnerable to neuron loss observed in Alzheimer disease. But she cautioned that controlled clinical trials would be needed to determine whether estrogen can prevent or slow the progression of Alzheimer disease. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Estrogen and Memory

JAMA , Volume 279 (4) – Jan 28, 1998

Estrogen and Memory

Abstract

Researchers at the National Institute on Aging have another reason for postmenopausal women to consider estrogen replacement therapy: it may help slow normal, age-related declines in memory. In the December issue of Neurology, the researchers reported on 288 women enrolled in the Baltimore Longitudinal Study of Aging between 1978 and 1994. They compared scores on a visual memory test taken by 116 women receiving estrogen therapy with the scores of 172 women who had never used any type of...
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Publisher
American Medical Association
Copyright
Copyright © 1998 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.279.4.262-JQU71030-3-1
Publisher site
See Article on Publisher Site

Abstract

Researchers at the National Institute on Aging have another reason for postmenopausal women to consider estrogen replacement therapy: it may help slow normal, age-related declines in memory. In the December issue of Neurology, the researchers reported on 288 women enrolled in the Baltimore Longitudinal Study of Aging between 1978 and 1994. They compared scores on a visual memory test taken by 116 women receiving estrogen therapy with the scores of 172 women who had never used any type of hormone replacement. On average, the women taking estrogen scored about 2 fewer errors than women who were never treated with estrogen, which the researchers said was a significant difference. They also noted that the study was the first to document the effect of estrogen on visual memory; previous studies have indicated that estrogen may have an effect on verbal memory. Susan Resnick, PhD, principal investigator of the study, said animal studies have shown that estrogen can directly affect structural characteristics of neurons in regions of the brain that are vulnerable to neuron loss observed in Alzheimer disease. But she cautioned that controlled clinical trials would be needed to determine whether estrogen can prevent or slow the progression of Alzheimer disease.

Journal

JAMAAmerican Medical Association

Published: Jan 28, 1998

Keywords: estrogen,memory

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