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Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore

Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore Key PointsQuestionWhat was the initial experience in Singapore with the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)? FindingsIn this descriptive case series of the first 18 patients diagnosed with SARS-CoV-2 infection in Singapore between January 23 and February 3, 2020, clinical presentation was a respiratory tract infection with prolonged viral shedding from the nasopharynx of 7 days or longer in 15 patients (83%). Supplemental oxygen was required in 6 patients (33%), 5 of whom were treated with lopinavir-ritonavir, with variable clinical outcomes following treatment. MeaningThese findings provide clinical features and course among patients diagnosed with SARS-CoV-2 infection in Singapore. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

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Publisher
American Medical Association
Copyright
Copyright 2020 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2020.3204
Publisher site
See Article on Publisher Site

Abstract

Key PointsQuestionWhat was the initial experience in Singapore with the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)? FindingsIn this descriptive case series of the first 18 patients diagnosed with SARS-CoV-2 infection in Singapore between January 23 and February 3, 2020, clinical presentation was a respiratory tract infection with prolonged viral shedding from the nasopharynx of 7 days or longer in 15 patients (83%). Supplemental oxygen was required in 6 patients (33%), 5 of whom were treated with lopinavir-ritonavir, with variable clinical outcomes following treatment. MeaningThese findings provide clinical features and course among patients diagnosed with SARS-CoV-2 infection in Singapore.

Journal

JAMAAmerican Medical Association

Published: Apr 21, 2020

References