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Epibulbar Malignant Melanoma in a Black Patient

Epibulbar Malignant Melanoma in a Black Patient Abstract • A 53-year-old black woman showed increasing epibulbar pigmentation following recurrent episcleritis at the same location. A biopsy was refused until vision was lost and a large black mass protruded from the globe and invaded the superficial cornea. Exenteration was performed and histological examination disclosed a malignant melanoma of the cornea with an adjacent intraepithelial conjunctival melanoma. We believe that the tumor arose in an area of acquired melanosis of the perilimbal conjunctiva and that secondary spread into adjacent superficial cornea occurred. Epibulbar malignant melanomas are uncommon conjunctival tumors in the general population and are especially rare in blacks. References 1. Third National Cancer Survey—Advanced Three Year Report: 1969-1971 Incidence , publication No. 74-637. Bethesda, Md, Biometry Branch, National Cancer Institute, 1974. 2. Yanoff M, Fine BS: Ocular Pathology . New York, Harper & Row Publishers Inc, 1975, pp 635, 657. 3. Lewis PM, Zimmerman LE: Delayed recurrences of malignant melanomas of the bulbar conjunctiva . Am J Ophthalmol 45:536-543, 1958. 4. Duke-Elder S: System of Ophthalmology: Part 2. Diseases of the Outer Eye , vol 8. St Louis, CV Mosby Co, 1965, p 1220. 5. Kielar R: Limbal melanoma in a Negro . Arch Ophthalmol 87:392-395, 1972.Crossref 6. Ash JE: Epibulbar tumors . Am J Ophthalmol 33:1203-1219, 1950. 7. Welsh NH, Jhatery Y: Malignant melanoma of the cornea in an African patient . Am J Ophthalmol 72:796-800, 1971. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Epibulbar Malignant Melanoma in a Black Patient

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Publisher
American Medical Association
Copyright
Copyright © 1979 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1979.01020010162016
Publisher site
See Article on Publisher Site

Abstract

Abstract • A 53-year-old black woman showed increasing epibulbar pigmentation following recurrent episcleritis at the same location. A biopsy was refused until vision was lost and a large black mass protruded from the globe and invaded the superficial cornea. Exenteration was performed and histological examination disclosed a malignant melanoma of the cornea with an adjacent intraepithelial conjunctival melanoma. We believe that the tumor arose in an area of acquired melanosis of the perilimbal conjunctiva and that secondary spread into adjacent superficial cornea occurred. Epibulbar malignant melanomas are uncommon conjunctival tumors in the general population and are especially rare in blacks. References 1. Third National Cancer Survey—Advanced Three Year Report: 1969-1971 Incidence , publication No. 74-637. Bethesda, Md, Biometry Branch, National Cancer Institute, 1974. 2. Yanoff M, Fine BS: Ocular Pathology . New York, Harper & Row Publishers Inc, 1975, pp 635, 657. 3. Lewis PM, Zimmerman LE: Delayed recurrences of malignant melanomas of the bulbar conjunctiva . Am J Ophthalmol 45:536-543, 1958. 4. Duke-Elder S: System of Ophthalmology: Part 2. Diseases of the Outer Eye , vol 8. St Louis, CV Mosby Co, 1965, p 1220. 5. Kielar R: Limbal melanoma in a Negro . Arch Ophthalmol 87:392-395, 1972.Crossref 6. Ash JE: Epibulbar tumors . Am J Ophthalmol 33:1203-1219, 1950. 7. Welsh NH, Jhatery Y: Malignant melanoma of the cornea in an African patient . Am J Ophthalmol 72:796-800, 1971.

Journal

Archives of Ophthalmology – American Medical Association

Published: Feb 1, 1979

References

  • Third National Cancer Survey—Advanced Three Year Report: 1969-1971 Incidence
  • Ocular Pathology
    Yanoff M, Fine BS
  • Delayed recurrences of malignant melanomas of the bulbar conjunctiva
    Lewis PM, Zimmerman LE
  • System of Ophthalmology: Part 2. Diseases of the Outer Eye
    Duke-Elder S
  • Limbal melanoma in a Negro
    Kielar R
  • Epibulbar tumors
    Ash JE
  • Malignant melanoma of the cornea in an African patient
    Welsh NH, Jhatery Y