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Enzymatic Zonulolysis in Lens Extraction

Enzymatic Zonulolysis in Lens Extraction Abstract Between January, 1958, and May, 1960, I performed 757 intracapsular lens extractions with the aid of enzymatic zonulolysis. This clinical experience and that of other authors has shown that enzymatic zonulolysis simplifies operative technique and increases the percentage of intracapsular lens extractions. Enzymatic zonulolysis has been adopted by surgeons from all parts of the world since the first report on this subject.1 The statistics of these cases have been presented in other meetings. This paper will stress the complications and their prevention. Several authors2 mention complications, such as intensive and persistent striate keratitis; massive liberation of iris pigment; hyaloid rupture; secondary glaucoma; retinal detachment, and so forth. Such complications have been exceptional in this series. Experience has shown that they are not connected with the use of α-chymotrypsin and are easily avoided by careful surgical technique. However, a higher incidence of complications resulting from poor wound healing has References 1. Barraquer, J.: Zonulolisis enzimática: Contribución a la cirugía del cristalino (Nota previa) , An. Med. Cir. 38:255, 1958. 2. Weekers, R.; Lavergne, G., and Stassart-Hourlay, C.: Avantages et inconvénients de la zonulolyse enzymatique dans l'extraction du cristallin cataracté , Bull. Soc. Belg. Ophtal. 120:539, 1958. 3. Bedrossian, R. H.: Alpha-Chymotrypsin: Its Effect on the Rabbit Zonule, Lens Capsule, and Corneal Wound Healing , A.M.A. Arch. Ophthal. 62:216, 1959.Crossref 4. Schwartz, B., and Schwartz, J. B.: A Review of the Biochemistry and Pharmacology of Alpha-Chymotrypsin , Trans. Amer. Acad., Ophthal. Otolaryng. (Jan.-Feb.) , 1960. 5. Fink, A. I.; Bernstein, H. N., and Binkhorst, D.: The Effect of Alpha-Chymotrypsin on Corneal Wound Healing , Arch. Ophthal. 64:104, 1960.Crossref 6. Legrand, J.: Film presented before the 66th Congress of the French Ophthalmological Society, 1959. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Enzymatic Zonulolysis in Lens Extraction

Archives of Ophthalmology , Volume 66 (1) – Jul 1, 1961

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Publisher
American Medical Association
Copyright
Copyright © 1961 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1961.00960010008004
Publisher site
See Article on Publisher Site

Abstract

Abstract Between January, 1958, and May, 1960, I performed 757 intracapsular lens extractions with the aid of enzymatic zonulolysis. This clinical experience and that of other authors has shown that enzymatic zonulolysis simplifies operative technique and increases the percentage of intracapsular lens extractions. Enzymatic zonulolysis has been adopted by surgeons from all parts of the world since the first report on this subject.1 The statistics of these cases have been presented in other meetings. This paper will stress the complications and their prevention. Several authors2 mention complications, such as intensive and persistent striate keratitis; massive liberation of iris pigment; hyaloid rupture; secondary glaucoma; retinal detachment, and so forth. Such complications have been exceptional in this series. Experience has shown that they are not connected with the use of α-chymotrypsin and are easily avoided by careful surgical technique. However, a higher incidence of complications resulting from poor wound healing has References 1. Barraquer, J.: Zonulolisis enzimática: Contribución a la cirugía del cristalino (Nota previa) , An. Med. Cir. 38:255, 1958. 2. Weekers, R.; Lavergne, G., and Stassart-Hourlay, C.: Avantages et inconvénients de la zonulolyse enzymatique dans l'extraction du cristallin cataracté , Bull. Soc. Belg. Ophtal. 120:539, 1958. 3. Bedrossian, R. H.: Alpha-Chymotrypsin: Its Effect on the Rabbit Zonule, Lens Capsule, and Corneal Wound Healing , A.M.A. Arch. Ophthal. 62:216, 1959.Crossref 4. Schwartz, B., and Schwartz, J. B.: A Review of the Biochemistry and Pharmacology of Alpha-Chymotrypsin , Trans. Amer. Acad., Ophthal. Otolaryng. (Jan.-Feb.) , 1960. 5. Fink, A. I.; Bernstein, H. N., and Binkhorst, D.: The Effect of Alpha-Chymotrypsin on Corneal Wound Healing , Arch. Ophthal. 64:104, 1960.Crossref 6. Legrand, J.: Film presented before the 66th Congress of the French Ophthalmological Society, 1959.

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Jul 1, 1961

References