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Enhanced Vertical Rectus Contractility by Magnetic Resonance Imaging in Superior Oblique Palsy

Enhanced Vertical Rectus Contractility by Magnetic Resonance Imaging in Superior Oblique Palsy CLINICAL SCIENCES Enhanced Vertical Rectus Contractility by Magnetic Resonance Imaging in Superior Oblique Palsy Robert A. Clark, MD; Joseph L. Demer, MD, PhD Objective: To seek evidence for causative secondary Results: In central gaze, the paretic SO was significantly changes in extraocular muscle volume, cross-sectional atrophic (P .001) and the contralesional superior rec- tus (SR) was significantly hypertrophic (P = .02). Across area, and contractility in superior oblique (SO) palsy using the range of vertical duction from supraduction to infra- magnetic resonance imaging, given that vertical devia- duction, both the contralesional SR (P = .04) and inferior tions in SO palsy greatly exceed those explained by loss rectus (P = .001) exhibited significantly supernormal con- of SO vertical action alone. tractile changes in maximum cross-sectional area. Con- tractile changes in the ipsilesional SR and inferior rectus Methods: High-resolution, quasi-coronal orbital mag- exhibited a similar but insignificant trend (.08P .12). netic resonance images in target-controlled central gaze, supraduction, and infraduction were obtained in 12 pa- Conclusions: Central gaze hypertrophy of the contra- tients with chronic unilateral SO palsy and 36 age- lesional SR may be secondary to chronic excess innerva- matched healthy volunteers using an 8-cm field of view tion http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Ophthalmology American Medical Association

Enhanced Vertical Rectus Contractility by Magnetic Resonance Imaging in Superior Oblique Palsy

Clark, Robert A.; Demer, Joseph L.
JAMA Ophthalmology , Volume 129 (7) – Jul 1, 2011
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References (22)

Publisher
American Medical Association
Copyright
Copyright 2011 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6165
eISSN
2168-6173
DOI
10.1001/archophthalmol.2011.152
pmid
21746981
Publisher site
See Article on Publisher Site

Abstract

CLINICAL SCIENCES Enhanced Vertical Rectus Contractility by Magnetic Resonance Imaging in Superior Oblique Palsy Robert A. Clark, MD; Joseph L. Demer, MD, PhD Objective: To seek evidence for causative secondary Results: In central gaze, the paretic SO was significantly changes in extraocular muscle volume, cross-sectional atrophic (P .001) and the contralesional superior rec- tus (SR) was significantly hypertrophic (P = .02). Across area, and contractility in superior oblique (SO) palsy using the range of vertical duction from supraduction to infra- magnetic resonance imaging, given that vertical devia- duction, both the contralesional SR (P = .04) and inferior tions in SO palsy greatly exceed those explained by loss rectus (P = .001) exhibited significantly supernormal con- of SO vertical action alone. tractile changes in maximum cross-sectional area. Con- tractile changes in the ipsilesional SR and inferior rectus Methods: High-resolution, quasi-coronal orbital mag- exhibited a similar but insignificant trend (.08P .12). netic resonance images in target-controlled central gaze, supraduction, and infraduction were obtained in 12 pa- Conclusions: Central gaze hypertrophy of the contra- tients with chronic unilateral SO palsy and 36 age- lesional SR may be secondary to chronic excess innerva- matched healthy volunteers using an 8-cm field of view tion

Journal

JAMA Ophthalmology – American Medical Association

Published: Jul 1, 2011

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